ArticleClinical kidney journal2026
Alfacalcidol plus calcium versus cholecalciferol in glucocorticoid-exposed children with nephrotic syndrome: a randomized controlled trial.
Article in Clinical kidney journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Updated perspectives on vitamin D deficiency, screening, supplementation and clinical guidance.Cardiovascular diabetology. Endocrinology reports · 2026Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study sought to explore the bone metabolism clinical features of pediatric nephrotic syndrome (NS) patients receiving glucocorticoid (GC) therapy and evaluate the bone-protective and renal-protective efficacy of alfacalcidol in this cohort. Methods: A prospective randomized cohort study was conducted at the Department of Nephrology, Guangzhou Women and Children's Medical Center, enrolling 86 children from January 2021 to June 2022. Participants were randomized into two groups ( Results: Multivariate regression identified cumulative GC dose as a risk factor for BMD reduction, while alfacalcidol treatment correlated with BMD improvement. Lumbar spine BMD increased by 0.028 ± 0.008 g/cm² in the alfacalcidol group versus 0.002 ± 0.008 g/cm² decrease in the control group ( Conclusions: Alfacalcidol may have potential bone-protective and renal-protective effects in pediatric NS patients undergoing GC therapy (Trial registration: ChiCTR2200055790).
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