Evidence map›Paper›PMID 41948270›Full record

ArticleCureus2026

Pacemaker Lead-Associated Innominate Vein Thrombosis Despite Non-vitamin K Oral Anticoagulant (NOAC) Therapy: An Incidental CT Finding.

Neeraj Joshi, Rachel Hallam, Zaw Nyein Aye, Harriet Guthrie, Md Mahmud Hasan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neeraj JoshiCardiology, East Kent Hospitals University NHS Foundation Trust, Queen Elizabeth The Queen Mother (QEQM) Hospital, Margate, GBR.
Rachel HallamMedicine, East Kent Hospitals University NHS Foundation Trust, Queen Elizabeth The Queen Mother (QEQM) Hospital, Margate, GBR.
Zaw Nyein AyeMedicine, East Kent Hospitals University NHS Foundation Trust, Queen Elizabeth The Queen Mother (QEQM) Hospital, Margate, GBR.
Harriet GuthrieMedicine, East Kent Hospitals University NHS Foundation Trust, Queen Elizabeth The Queen Mother (QEQM) Hospital, Margate, GBR.
Md Mahmud HasanMedicine, East Kent Hospitals University NHS Foundation Trust, Queen Elizabeth The Queen Mother (QEQM) Hospital, Margate, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venous thrombosis occurring despite therapeutic non-vitamin K oral anticoagulant (NOAC) therapy represents a diagnostic and management challenge, particularly in patients with indwelling cardiac implantable electronic devices. Pacemaker-associated central venous thrombosis is a recognized but often underdiagnosed finding due to its frequently asymptomatic presentation. We report the case of an older adult with a permanent pacemaker implanted approximately 10 months earlier who was undergoing evaluation for unexplained weight loss, in whom cross-sectional imaging incidentally revealed left innominate vein thrombosis without clinical features of venous obstruction. The patient was receiving full-dose NOAC therapy for atrial fibrillation, with good adherence and no alternative provoking factors identified. This case highlights the importance of recognizing venous thrombosis in patients with cardiac implantable electronic devices despite therapeutic anticoagulation and supports a careful, mechanism-based approach to evaluation and management in similar situations.

Indexed as

anticoagulationbrachiocephalic (innominate) vein thrombosiscase report of educational interventiondevice-related thrombosis (drt)incidental radiological findingnoacspermanent pacemaker (ppm) complicationwarfarin

Identifiers

PMID41948270
PMCPMC13052664

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.