Optimizing platelet transfusion thresholds based on TEG maximum clot strength (MA value) to reduce platelet usage and improve patient outcomes in liver transplantation: a cohort study.

Pingping Qi, Chunli Wu, Jianyue Zhou, Rong Tang

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

4 authors.

Pingping QiBlood Transfusion Department, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Chunli WuBlood Transfusion Department, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China.

Jianyue ZhouBlood Transfusion Department, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Rong TangRuikang Hospital Affiliated to Guangxi University of Chinese Medicine Intensive Care Unit, Nanning, Guangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liver transplantation (LT) is a highly complex procedure often requiring substantial blood product transfusions. Conventional platelet transfusion practices rely on static platelet count thresholds, potentially leading to overuse and associated risks. Thromboelastography (TEG) offers dynamic assessment of clotting, particularly through the Maximum Clot Strength (MA) value, which may optimize platelet transfusion thresholds and improve outcomes. Methods: This retrospective cohort study analyzed 231 patients who underwent LT between January 2019 and December 2023. Patients were divided into the TEG group ( Results: After propensity matching, the TEG group demonstrated significant reductions in platelet transfusions on postoperative days 1 and 3 compared to the CPCT group (36.9 vs. 61.7% on day 1, Conclusion: Implementing TEG-guided platelet transfusion strategies in LT significantly reduces platelet use and improves patient QOL by providing real-time functional hemostasis assessments.

Indexed as

coagulopathyliver transplantationmaximum clot strengthplatelet transfusionpostoperative quality of life

Identifiers

PMID41948583

DOI10.3389/fmed.2026.1727144

PMCPMC13050902

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.