Evidence map›Paper›PMID 41948658›Full record

ArticleHealth science reports2026

Characteristics of Patients With Severe Hypochloremia in the Emergency Department: A Single Center Retrospective Study.

Teppei Koyama, Naohiko Imai, Yohei Kita, Ryuichiro Makinouchi, Shinji Machida, Sayuri Shirai

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teppei KoyamaDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.
Naohiko ImaiDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.ORCID https://orcid.org/0000-0001-9984-2889
Yohei KitaDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.
Ryuichiro MakinouchiDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.
Shinji MachidaDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.
Sayuri ShiraiDivision of Nephrology and Hypertension, Department of Internal Medicine St. Marianna University Yokohama Seibu Hospital.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Hypochloremia is an electrolyte disturbance in which the serum chloride concentration is abnormally low. Hypochloremia is associated with poor outcomes in critically ill patients in the intensive care unit (ICU) and coronary care unit (CCU), but little is known about its prevalence and prognosis in the emergency department (ED). We investigated the real-world prevalence and prognosis of severe hypochloremia in the ED. Methods: All adult patients (18 years old or older) with serum chloride levels measured at our ED between 2018 and 2023 were included. Hypochloremia and severe hypochloremia were defined as a serum chloride level of ≦97 and ≦80 mEq/L, respectively. Information collected included age, sex, serum chloride, and serum creatinine. Results: 11,065 adult patients had their serum chloride measured at the ED. The mean age of patients was 67 ± 20 years, and 53% were male. The mean serum creatinine and eGFR were 1.4 ± 1.8 mg/dL and 66 ± 48 mL/min/1.73 m Conclusion: The 30-day mortality of patients presenting to the ED with severe hypochloremia was high. Hypochloremia may be associated with poor short-term outcomes in patients presenting to the ED.

Indexed as

emergency departmenthypochloremiamortalityprevalence

Identifiers

PMID41948658
PMCPMC13051867

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.