SynthesisFrontiers in pharmacology2026
Mechanisms of active metabolites from traditional Chinese medicine in osteoarthritis: a critical review.
Synthesis in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Mechanisms of resveratrol in cartilage injury repair and protection: A review.The Journal of international medical research · 2026Review
- Psychological stress and gut microbiota regulation of osteoarthritis progression: mechanisms and therapeutic strategies.Frontiers in microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is a prevalent degenerative joint disease with multifactorial pathogenesis and no cure. Traditional Chinese Medicine (TCM) is widely used in OA management, and accumulating research suggests that bioactive metabolites (formerly termed active components) from TCM botanical drugs can modulate key pathological processes in OA. Traditional Chinese medicine has an important role in OA management owing to its relatively low incidence of adverse effects, affordability, and multi-target therapeutic actions. In this review, we systematically searched PubMed and Web of Science (2010-2025) for studies on TCM-derived metabolites in OA using keywords such as "osteoarthritis," "Traditional Chinese Medicine," "active constituent," and "mechanism." Relevant
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.