ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Application of Novel Thrombosis Scale in Fracture Related Lower Extremity Deep Venous Thrombosis.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BackgroundLower limb fractures with peripheral deep venous thrombosis (DVT) are common, yet unified stratified treatment standards are lacking. Quantifying thrombus burden guides decisions like inferior vena cava (IVC) filter implantation or anticoagulation. Existing scoring systems rarely integrate peripheral vein anatomy and imaging features, limiting clinical utility.ObjectiveTo develop a dual-dimensional scoring scale for thrombus burden quantification and validate its value in guiding stratified treatment.MethodsA retrospective study of 68 fracture-related DVT patients (Suzhou TCM Hospital, Nov 2022-Nov 2023) was conducted. A 0-25 point scale integrating 7 peripheral veins and muscular venous plexus features was designed. Receiver operating characteristic (ROC) analysis identified the optimal IVC filter cutoff; patients were split into filter group (≥4 points, n = 21, filter + anticoagulation) and anticoagulation group (<4 points, n = 47, single anticoagulation). 1:2 PSM eliminated baseline confounding; adverse events, scores and coagulation indices were compared.ResultsNo adverse events or filter-related complications occurred. Both groups had significant post-treatment score and D-dimer reductions (all
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