Evidence map›Paper›PMID 41949488›Full record

SynthesisJournal of Alzheimer's disease : JAD2026

The interventional effect of acupuncture on overall cognitive function in Alzheimer's disease spectrum disorders: A meta-analysis.

Yifan Chen, Shenggang Zhao, Fenglei Yang, Ya Wang, Zhenxiang Han, Fang Han, Zhiqun Wang, Zhenbo Chen, Kai Sun, Peipeng Liang and 1 more

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yifan ChenDepartment of Radiology, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, China.ORCID 0000-0001-9814-3234
Shenggang ZhaoTechnical Research Institute, Beijing Wanfang Medical Information Technology Co., Ltd, Beijing, China.
Fenglei YangTechnical Research Institute, Beijing Wanfang Medical Information Technology Co., Ltd, Beijing, China.
Ya WangSchool of Psychology, Capital Normal University, Beijing, China.ORCID 0000-0001-5764-6740
Zhenxiang HanDepartment of Neurology and Rehabilitation, Seventh People's Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China.ORCID 0000-0003-1963-580X
Fang HanInstitute of Radiology and Nuclear Medicine, Dalian University, Dalian, China.ORCID 0009-0000-7566-2912
Zhiqun WangDepartment of Radiology, Aerospace Center Hospital, Beijing, China.ORCID 0000-0001-9608-0962
Zhenbo ChenDepartment of Radiology, Beijing Bo'ai Hospital, China Rehabilitation Research Center, Beijing, China.ORCID 0000-0002-3967-6564
Kai SunLonggang Institute of Medical Imaging, Shantou University Medical College, Shenzhen, China.ORCID 0000-0002-1217-4265
Peipeng LiangSchool of Psychology, Capital Normal University, Beijing, China.ORCID 0009-0007-3318-5370
Kuncheng LiDepartment of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID 0000-0002-1898-3979

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAlzheimer's disease (AD) and mild cognitive impairment (MCI) cause progressive cognitive decline, with Western medicine only alleviating symptoms at present. Acupuncture shows potential for these disorders, but existing studies have inconsistent results.ObjectiveTo examine the effect of acupuncture on overall cognitive function in patients with AD and MCI via meta-analysis.MethodLiterature from six databases on acupuncture, AD, and MCI was searched. Meta-analyses and moderator analyses were performed using Comprehensive Meta Analysis V3.0.Results52 randomized controlled trials (RCTs) involving 3362 AD/MCI patients were included. Results showed that acupuncture alone outperformed blank or placebos (

Indexed as

Acupuncture TherapyAlzheimer DiseaseCognitionCognitive DysfunctionCognitive EnhancementHumansRandomized Controlled Trials as TopicTreatment OutcomeacupunctureAlzheimer's diseasemeta-analysismild cognitive impairmentrandomized controlled trials

Identifiers

PMID41949488
PMCPMC13219789

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.