Evidence map›Paper›PMID 41951589›Full record

ArticleCell death & disease2026

Perforin-2 enhances antigen-specific CTL immune response by promoting cross presentation.

Zhi-Kai Zha, Cheng-Jie Deng, Ling-Jun Shen, Ling-Zhen Liu, Yun-Xiao Huang, Yan-Hong Li, Li Lv, Ke Zhang, Lin-Shuang Chen, Fei-Er Chen and 1 more

Abstract read
In one paragraph

Article in Cell death & disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhi-Kai Zha *Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Cheng-Jie Deng *The Center of Experimental Teaching, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Ling-Jun Shen *Department of Tuberculosis, Yunnan Clinical Medical Center for Infectious Diseases, the Third People's Hospital of Kunming (The Sixth Affiliated Hospital of Dali University), Kunming, China.
Ling-Zhen Liu *Yunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Yun-Xiao HuangYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Yan-Hong LiYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Li LvYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Ke ZhangYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Lin-Shuang ChenYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Fei-Er ChenYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China.
Sheng-An LiYunnan Provincial Key Laboratory of Public Health and Bio-safety & Department of Pathogen Biology and Immunology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, China. lishengan@163.com.ORCID http://orcid.org/0000-0002-9654-076X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antigen cross-presentation is essential for initiating CD8

Indexed as

Cross-PrimingPore Forming Cytotoxic ProteinsT-Lymphocytes, CytotoxicAnimalsAntigen PresentationCD8-Positive T-LymphocytesDendritic CellsMiceMice, Inbred C57BLMice, KnockoutPore Forming Cytotoxic Proteins

Identifiers

PMID41951589
PMCPMC13187254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.