ArticleRSC advances2026
Potential screening of oral squamous cell carcinoma using microRNA geno-assay by electrochemical sensing: a new platform in biosensor technology.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early-stage diagnosis of oral squamous cell carcinoma (OSCC), a prominent global cause of mortality, is crucial for minimizing morbidity and mortality rates. MicroRNA-423-5p is chosen for effective identification of OSCC because of its high specificity in the Receiver Operating Characteristic (ROC) curve, enabling precise diagnosis of oral cancer (OC) in human biofluids. This work introduces a novel label-free electrochemical platform for the non-invasive recognition of microRNA-423-5p in human saliva samples. The monitoring is achieved by a DNA-based bioassay. In order to achieve this objective, polychitosan (P(CS)) was electropolymerized on the surface of a glassy carbon electrode (GCE) and used as a high-potential capturing layer on the surface of the GCE. Also, triangular silver nanoparticles (TA-AgNPs) were used for stable immobilization of probe-DNA. This allowed for the effective immobilization of thiolated DNA sequences
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.