Evidence map›Paper›PMID 41956786›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2026

[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease].

S T Wu, X L Lu

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S T WuDepartment of Gastroenterology, Shanghai Pudong Hospital-Fudan University Pudong Medical Center, Shanghai 201399, China.
X L LuDepartment of Gastroenterology, Shanghai Pudong Hospital-Fudan University Pudong Medical Center, Shanghai 201399, China.

Funding

Natural Science Foundation of China 82470597The Clinical Medicine Emerging Speciality (or Specific Disease) Program of the Pudong New Area Health Commission 2025-PWXZ-05
6 · The paper itself

Abstract

Metabolic associated fatty liver disease (MAFLD) is the main cause of chronic liver disease and hepatic dysfunction, with its incidence rate increasing year by year in China. The gut microbiota and its metabolites promote the occurrence and development of diseases by affecting host metabolism, immunity, and inflammatory responses. Current research focuses primarily on the single-dimension or unidirectional effects of metabolism, immunity, and inflammation, with a lack of comprehensive recognition about the complex regulation of their interaction in MAFLD. Therefore, this paper summarizes the effects of gut microbiota on the host and liver from three aspects: metabolism regulation, immunity, and inflammatory response. Additionally, it systematically reveals the multidimensional regulatory mechanism of gut microbiota in MAFLD, providing a basis for understanding the pathogenesis of MAFLD and formulating precise therapies.

Indexed as

Fatty LiverGastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsHumansInflammationLiver

Identifiers

PMID41956786
PMCPMC13076384

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.