Evidence map›Paper›PMID 41957120›Full record

ArticleScientific reports2026

Prevalence and risk factors of hepatitis B, hepatitis C, and syphilis among reproductive-age adults in the Tigray region, Northern Ethiopia: a community-based cross-sectional study.

Gebretsadik Berhe, Goyitom Gebremedhn Gebru, Mohamedawel Mohamedniguss Ebrahim, Tesfay Gebregzabher Gebrehiwet, Hayelom Kahsay, Tsegay Hadgu, Amanuel Haile, Gebrecherkos Teame Gebrehiwot, Hadish Bekuretsion Areeya, Gebremichael Gebreegziabher Teklu and 16 more

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Gebretsadik BerheCollege of Health Sciences, Mekelle University, Tigray, Ethiopia. gebretsadik_b@yahoo.com.ORCID http://orcid.org/0000-0002-5610-1383
Goyitom Gebremedhn GebruTigray Health Research Institute, Tigray, Ethiopia.
Mohamedawel Mohamedniguss EbrahimCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.ORCID http://orcid.org/0000-0003-4556-2579
Tesfay Gebregzabher GebrehiwetCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.
Hayelom KahsayTigray Health Research Institute, Tigray, Ethiopia.
Tsegay HadguTigray Health Research Institute, Tigray, Ethiopia.
Amanuel HaileTigray Regional Health Bureau, Tigray, Ethiopia.
Gebrecherkos Teame GebrehiwotTigray Health Research Institute, Tigray, Ethiopia.
Hadish Bekuretsion AreeyaTigray Health Research Institute, Tigray, Ethiopia.
Gebremichael Gebreegziabher TekluTigray Health Research Institute, Tigray, Ethiopia.
Mache TsadikCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.
Brhane AyeleTigray Health Research Institute, Tigray, Ethiopia.
Letebrhan WeldemhretTigray Health Research Institute, Tigray, Ethiopia.
Kibriti Mehari KidaneTigray Health Research Institute, Tigray, Ethiopia.
Kiros DemozTigray Health Research Institute, Tigray, Ethiopia.
Ataklti Gessesse TekaTigray Health Research Institute, Tigray, Ethiopia.
Nega MamoTigray Health Research Institute, Tigray, Ethiopia.
Degnesh Negash ZigtaTigray Health Research Institute, Tigray, Ethiopia.
Etsay Weldekidan TsegayTigray Health Research Institute, Tigray, Ethiopia.
Mesfin Tesfay ZelalemTigray Health Research Institute, Tigray, Ethiopia.
Lemelm Legesse WeldegabrielTigray Health Research Institute, Tigray, Ethiopia.
Asfawosen Aregay BerheTigray Health Research Institute, Tigray, Ethiopia.
Mebrahtu Teweldemedhin ShfareCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.
Haftom Temesgen AbebeCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.
Tsehaye Asmelash DejeneCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.
Araya Gebreyesus WasihunCollege of Health Sciences, Mekelle University, Tigray, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In World Health Organization’s (WHO) 2024 Global Hepatitis Report, viral hepatitis is the second leading infectious cause of death globally, and syphilis remains a major public health concern, particularly in sub-Saharan Africa. Ethiopia ranks among the countries most heavily burdened by hepatitis B virus (HBV) and hepatitis C virus (HCV). However, community-level data for the Ethiopia’s Tigray region is limited. To assess sero-prevalence and risk factors of HBV, HCV, and syphilis among the general population in the Tigray region, we conducted a cross-sectional survey from June 1 to September 30, 2024. Females aged 15–49 and men aged 15–54 were enrolled. A total of 6,010 study participants were recruited into the study. Data were collected via structured questionnaire using Open Data Kit (ODK) and venous blood samples were tested for infections. Binary logistic regression was used to identify factors associated with HBV and syphilis. The overall positivity rate was 3.6% (95% CI: 3.14 − 4.08%), with hepatitis B (2.1%) being the most prevalent, followed by syphilis (1.5%) and hepatitis C (0.2%). HBV was significantly higher in the Southeast Zone (Adjusted Odds Ratio, AOR = 2.04, 95% Confidence Interval, CI: 1.20 − 3.47). Slightly higher infection rates were observed among males, divorced individuals, student occupation and rural residents, but these differences were not statistically significant after adjustment. Syphilis sero-positivity was associated with age 35–54 (AOR = 3.43; 95% CI: 1.34–8.74), age 45–54 years (AOR = 6.77; 95% CI: 2.49–18.36), widowhood (AOR = 8.22; 95% CI: 1.75–38.65), urban residence (AOR = 1.90; 95% CI: 1.04–3.49), and smaller family size (1–3 members; AOR = 3.21; 95% CI: 1.72–5.97). These data indicate the need for targeted public health interventions and continuing surveillance in high-risk areas and vulnerable populations. The study highlights critical gaps in community-level data and calls for greater regional surveillance of diseases.

Indexed as

Hepatitis BHepatitis CSyphilisAdolescentAdultCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsYoung AdultEthiopiaHBVHCVSero-prevalenceSyphilisTigray

Identifiers

PMID41957120
PMCPMC13213023

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.