ArticleCardiovascular diabetology2026
Diabetes-related differences in body composition and their prognostic value among patients with heart failure and preserved ejection fraction: a cardiac-MRI-based study.
Article in Cardiovascular diabetology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHeart failure and diabetes mellitus share common risk factors and can independently regulate the body composition profile of patients. Approximately one-third of patients with heart failure and preserved ejection fraction (HFpEF) have concomitant diabetes mellitus, but the additional impact of diabetes on the body composition of HFpEF patients and its associations with prognosis have not been explored.
methodsThis study included 281 HFpEF patients, among whom 87 had type 2 diabetes (T2DM). On the basis of their cardiac magnetic resonance (MR) images, regional adipose tissue (including subcutaneous, visceral and paracardial adipose tissue) as well as thoracic skeletal muscle were measured and compared between the diabetic and non-diabetic groups. Clinical endpoints were recorded and the predictive performance of body composition parameters and body mass index (BMI) for adverse events was assessed using multivariable Cox regression analysis in the overall HFpEF population and subgroups stratified by diabetes.
resultsHFpEF patients with concomitant diabetes were significantly older (65.06 ± 12.92 vs. 57.98 ± 14.44 years, p < 0.001). The LVEDV index and LVSV index were significantly lower in the T2DM group. The paracardial adipose tissue (ParaAT index) was noticeably greater in the T2DM group than in the non-T2DM group (76.21 vs. 65.60 ml/m
conclusionsConcomitant diabetes exacerbated paracardial adipose excess among HFpEF patients and worsened the association between body composition and adverse outcomes.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.