Evidence map›Paper›PMID 41958587›Full record

ReviewFrontiers in medicine2026

The multifaceted mechanisms of Tanshinone IIA in doxorubicin-induced cardiotoxicity.

Qinqin Wang, Danqi Zou, Huan Chen, Di Cui, Xupeng Huang, Yuqiu Chen, Yuxin Qi, Zheng Nan, Xiang Wang, Xiaoling Shang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qinqin Wang *College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Danqi Zou *College of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Huan ChenCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Di CuiCollege of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.
Xupeng HuangCollege of Traditional Chinese Medicine, Changchun University of Chinese Medicine, Changchun, China.
Yuqiu ChenCollege of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.
Yuxin QiCollege of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.
Zheng NanThe Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin, China.
Xiang WangCollege of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.
Xiaoling ShangCollege of Basic Medicine, Changchun University of Chinese Medicine, Changchun, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin (DOX)-induced cardiotoxicity significantly impairs patients' quality of life and long-term prognosis, and can lead to irreversible cardiac dysfunction and heart failure years or even decades after chemotherapy has ceased. Natural medicinal products represent a promising strategy for preventing or treating this cardiotoxicity, with

Indexed as

adriamycincardiac toxicitydrug delivery systempharmacological mechanism of actionTanshinone IIA

Identifiers

PMID41958587
PMCPMC13057525

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.