Evidence map›Paper›PMID 41958708›Full record

ArticleCancer communications (London, England)2026

Proliferation and Apoptosis Adaptor Protein 15 (PEA15), a Potential Oncogenic Regulator of VHL and HIF1A Identified through Proteomic Analysis in Hepatocellular Carcinoma.

Yun Seong Jeong, Ji-Hyun Shin, Soo Mi Kim, Bo Hwa Sohn, Sun Young Yim, Ji Hoon Kim, Jae Jun Shim, Sung Hwan Lee, Yun Shin Chun, Sunyoung S Lee and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer communications (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yun Seong JeongDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ji-Hyun ShinDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Soo Mi KimDepartment of Physiology, Institute of Medical Science, Jeonbuk National University Medical School, Jeonju, Jeonbuk, Korea.
Bo Hwa SohnDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sun Young YimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Ji Hoon KimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Jae Jun ShimDepartment of Internal Medicine, Kyung Hee University Hospital, Seoul, Korea.
Sung Hwan LeeDivision of Hepatobiliary and Pancreas, Department of Surgery, CHA Bundang Medical Center, CHA University, Sungnam, Korea.
Yun Shin ChunDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sunyoung S LeeDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Hui DaiDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ahmed KasebDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Koo Jeong KangDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Keimyung University Dongsan Medical Center, Daegu, Korea.
Holger K EltzschigDepartment of Anesthesiology, Critical Care and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
A Robert MacLeodIonis Pharmaceuticals, Carlsbad, CA, USA.
Xiaolin LuoIonis Pharmaceuticals, Carlsbad, CA, USA.
Alexey RevenkoIonis Pharmaceuticals, Carlsbad, CA, USA.
Youngsoo KimIonis Pharmaceuticals, Carlsbad, CA, USA.
Ju-Seog LeeDepartment of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID https://orcid.org/0000-0002-5666-9753

Funding

The University of Texas MD Anderson Cancer Center SPORE in Hepatocellular CarcinomaP50CA217674 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LAURA BERETTA, Ahmed Kaseb · 2023 to 2023
$2.8M
PEA15 IN DEVELOPMENT OF LIVER CANCER AND ITS THERAPEUTIC IMPLICATIONR01CA237327 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Ju-Seog Lee · 2022 to 2023
$701k
NCI NIH HHS P50 CA217674NCI NIH HHS R01 CA237327
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Apoptosis Regulatory ProteinsCarcinoma, HepatocellularHypoxia-Inducible Factor 1, alpha SubunitIntracellular Signaling Peptides and ProteinsLiver NeoplasmsVon Hippel-Lindau Tumor Suppressor ProteinAnimalsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMaleMiceMice, NudeProteomicsApoptosis Regulatory ProteinsHIF1A protein, humanHypoxia-Inducible Factor 1, alpha SubunitIntracellular Signaling Peptides and ProteinsPEA15 protein, humanVHL protein, humanVon Hippel-Lindau Tumor Suppressor Protein

Identifiers

PMID41958708
PMCPMC13058230

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.