Trajectories of total and domain-specific physical activity and vascular structure and function in mid-adulthood: the Childhood Determinants of Adult Health study.

Jack T Evans, Verity J Cleland, Seana Gall, Terence Dwyer, Alison J Venn, Rachel E Climie

Abstract read

In one paragraph

Article in European heart journal open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jack T EvansMenzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, Tasmania 7000, Australia.ORCID https://orcid.org/0000-0001-6204-4509

Verity J ClelandMenzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, Tasmania 7000, Australia.ORCID https://orcid.org/0000-0001-8358-3237

Seana GallMenzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, Tasmania 7000, Australia.ORCID https://orcid.org/0000-0002-5138-2526

Terence DwyerNuffield Department of Women's & Reproductive Health, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.ORCID https://orcid.org/0000-0002-2091-7663

Alison J VennMenzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, Tasmania 7000, Australia.ORCID https://orcid.org/0000-0001-7090-1398

Rachel E ClimieMenzies Institute for Medical Research, University of Tasmania, 17 Liverpool St, Hobart, Tasmania 7000, Australia.ORCID https://orcid.org/0000-0002-7960-360X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Physical activity is a target for early and ongoing cardiovascular health maintenance. However, relationships between life course trajectories of total activity and all comprising domains (leisure, transport, occupational, domestic) with vascular function and structure have not been examined. This study aimed to determine associations between life course activity trajectories and mid-adulthood vascular structure and function. Methods and results: Using the Australian Childhood Determinants of Adult Health Study [four time points (ages 9-49 years); 1985 baseline], latent class growth mixture modelling assessed life course trajectories of questionnaire-measured total and domain-specific activity ( Conclusion: This study was the first to assess life course trajectories of total and domain-specific activity against vascular structure and function. Findings highlight that maintaining high levels of leisure-time activity across the life course may be associated with better vascular structure in mid-adulthood.

Indexed as

Cohort studiesHeart disease risk factorsLife course perspectivesPaediatricsPhysical activity

Identifiers

PMID41958749

DOI10.1093/ehjopen/oeag038

PMCPMC13061350

What Socratic holds

Textmetadata

LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.