Evidence map›Paper›PMID 41959241›Full record

ArticlebioRxiv : the preprint server for biology2026

Genetic Identification of Dopamine Neurons Required for Circadian Food Anticipatory Activity in Mice.

Andrew P Villa, Jacqueline Trzeciak, Damien Wolfe, David E Ehichioya, Jeffrey Falkenstein, Justine T Wong, Lauren Dimalanta, Wyatt Kaiban, Jaskaran Dhanoa, Gregory Stevens and 9 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Andrew P VillaDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Jacqueline TrzeciakDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Damien WolfeDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
David E EhichioyaDepartment of Neuroscience; Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX; USA.
Jeffrey FalkensteinDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Justine T WongDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Lauren DimalantaDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Wyatt KaibanDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Jaskaran DhanoaDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Gregory StevensDivision of Biology and Bioengineering, California Institute of Technology, Pasadena, CA; USA.
Fernando GarciaDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Lori ScarpaDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Chris ChalfounDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.
Larry S ZweifelDepartment of Psychiatry and Behavioral Sciences, Department of Pharmacology, University of Washington, Seattle, United States.
Rajeshwar AwatramaniDepartment of Neurology, Northwestern University, Chicago, IL 60611, USA.
Richard D PalmiterHoward Hughes Medical Institute and Departments of Biochemistry and Genome Sciences, University of Washington, Seattle, WA, USA.
Martin DarvasDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Shin YamazakiDepartment of Neuroscience; Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX; USA.
Andrew D SteeleDepartment of Biological Sciences, California State Polytechnic University Pomona; Pomona, CA; USA.ORCID 0000-0001-8777-4970

Funding

Developmental underpinnings of substantia nigra vulnerabilityR01NS119690 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AWATRAMANI, RAJESHWAR B · 2021 to 2025
$2.4M
Neural circuitry and functional significance of extra-SCN pacemakersR01NS114527 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI YAMAZAKI, SHIN · 2020 to 2024
$1.9M
Broadening access with an Armamentarium Vector Core Powered by Inclusive Research Experiences - SUPPLEMENTU24MH131054 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GRADINARU, VIVIANA, SHAY, TIMOTHY FRANCIS · 2022 to 2024
$1.9M
Deciphering dopaminergic circuits required for food anticipatory activity in miceR16GM145576 · NIGMS · CALIFORNIA STATE POLY U POMONA · PI Andrew David Steele · 2023 to 2026
$819k
Investigating dopaminergic neuronal circuits mediating circadian entrainment to scheduled feedingSC3GM125570 · NIGMS · CALIFORNIA STATE POLY U POMONA · PI STEELE, ANDREW DAVID · 2018 to 2021
$441k
NIGMS NIH HHS R16 GM145576NIGMS NIH HHS SC3 GM125570NIMH NIH HHS U24 MH131054NINDS NIH HHS R01 NS114527NINDS NIH HHS R01 NS119690
6 · The paper itself

Abstract

Anticipating daily food availability is a conserved circadian behavior that persists even in animals lacking the suprachiasmatic nucleus, yet the neural substrates of this behavior remain poorly defined. Striatal dopamine signaling through D1 receptors promotes food anticipatory activity (FAA), but the dopaminergic neurons responsible are unknown. Here, we conditionally deleted

Identifiers

PMID41959241
PMCPMC13060229

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.