Evidence map›Paper›PMID 41959280›Full record

ArticlebioRxiv : the preprint server for biology2026

Defective transcription of AAGAG satellite DNA causes sex-ratio meiotic drive in

Tomohiro Kumon, Mami Nakamizo-Dojo, Amelie A Raz, Romain Lannes, Jaclyn M Fingerhut, Yukiko M Yamashita

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Tomohiro KumonWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.
Mami Nakamizo-DojoWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.
Amelie A RazWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.ORCID 0000-0002-4651-0626
Romain LannesWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.
Jaclyn M FingerhutWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.
Yukiko M YamashitaWhitehead Institute for Biomedical Research, Cambridge, MA02142, USA.ORCID 0000-0001-5541-0216

Funding

Combinatorial signal integration in the maintenance and renewal of adult germline stem cell fateK99GM154143 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI Amelie Raz · 2025 to 2026
$326k
Reprogramming towards a germline stem cell fateF32GM143850 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI RAZ, AMELIE · 2021 to 2023
$205k
NIGMS NIH HHS F32 GM143850NIGMS NIH HHS K99 GM154143
6 · The paper itself

Abstract

Male germ cells have complex transcriptomes, with a large fraction of the genome being transcribed. This includes protein-coding genes (often not translated), non-coding DNA, and repetitive DNA, such as transposons and satellite DNA, which are normally silenced as heterochromatin. The significance of such widespread transcription remains unknown. Here, we show that a heterochromatin protein, HP2, is required for the transcription of AAGAG satellite DNA in

Identifiers

PMID41959280
PMCPMC13060095

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.