Evidence map›Paper›PMID 41959337›Full record

ArticlebioRxiv : the preprint server for biology2026

Functional Exploration of African Colorectal Cancer Patients Using Personalised

Festus Adeyimika Oyeniyi, Favour Ayomide Oladokun, Abigael Abosede Ajayi, Abdulwasiu Ibrahim, Ruth Seyi Aladeloye, Opeyemi Abigail Akinfe, Funmilayo Rosemary Oludaiye, Thomas G Moens, Hammed A Badmos, Amos Olalekan Abolaji and 1 more

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In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Festus Adeyimika OyeniyiDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Favour Ayomide OladokunDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Abigael Abosede AjayiDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Abdulwasiu IbrahimDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Ruth Seyi AladeloyeDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Opeyemi Abigail AkinfeDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Funmilayo Rosemary OludaiyeDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Thomas G MoensSchool of Cancer Sciences, the University of Glasgow, Glasgow, UK.
Hammed A BadmosSchool of Cancer Sciences, the University of Glasgow, Glasgow, UK.
Amos Olalekan AbolajiDrosophila Research and Training Centre, A2 Salami Somade Estate, Basorun, Ibadan, Nigeria.
Ross CaganSchool of Cancer Sciences, the University of Glasgow, Glasgow, UK.ORCID 0000-0001-5297-450X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer across sub-Saharan Africa presents a growing global health burden, with increasing cases and mortality linked to late diagnosis, limited healthcare access and lack of effective treatments. African patients typically present with aggressive disease marked by distinct genomic signatures, indicating the need for targeted treatment approaches. We integrated genetic modelling, phenotypic scoring, imaging and biochemical analysis to explore how mutations found in individual Nigerian colorectal cancer patients influence drug responsiveness. We used the data from Cancer Genome Atlas to identify mutation profiles specific to Nigerian patients. We then generated ten stable

Indexed as

Colorectal cancerDrosophila melanogasterPersonalised medicineTargeted therapy

Identifiers

PMID41959337
PMCPMC13060073

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.