Evidence map›Paper›PMID 41959444›Full record

ArticlebioRxiv : the preprint server for biology2026

The nanoscale mobility of calcium channels is driven by readily releasable synaptic vesicles to support precise neurotransmission in live

Yunke Zhao, Dai Zhai, Fabien Pinaud

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yunke ZhaoDepartment of Biological Sciences, University of Southern California, 1050 Child Way, Los Angeles, CA 90089, USA.ORCID 0000-0002-4211-2137
Dai ZhaiDepartment of Biological Sciences, University of Southern California, 1050 Child Way, Los Angeles, CA 90089, USA.ORCID 0009-0003-7336-6839
Fabien PinaudDepartment of Biological Sciences, University of Southern California, 1050 Child Way, Los Angeles, CA 90089, USA.ORCID 0000-0002-4272-3616

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
CBI: Chemistry Biology InterfaceT32GM118289 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2016 to 2020
$1.2M
Nanoscale dynamics of voltage-gated calcium channels at presynaptic active zones in live C. elegansR21NS114911 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PINAUD, FABIEN · 2020 to 2020
$511k
NIGMS NIH HHS T32 GM118289NIH HHS P40 OD010440NINDS NIH HHS R21 NS114911
6 · The paper itself

Abstract

Precise neurotransmission requires voltage-gated calcium channels (VGCCs) to be tightly coupled with synaptic vesicles (SVs) at active zones (AZs). As VGCCs are mobile in the fluid presynaptic membrane, it remained unclear how they spatiotemporally align with SVs for reliable synaptic release. Using super-resolution imaging and single-molecule tracking in

Indexed as

Active zoneNanoscale diffusionSNARESuper-resolution imagingSynaptic vesicle releaseUNC-10UNC-13Voltage-gated calcium channels

Identifiers

PMID41959444
PMCPMC13060093

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.