Evidence map›Paper›PMID 41959909›Full record

ArticleFrontiers in oncology2026

Radiotherapy for low grade gliomas in children with neurofibromatosis type 1: when there is no other choice. Case Report.

Serafin Castellano-Damaso, Felisa Vazquez-Gomez, Marta Perez-Somarriba, Mercedes Muñoz-Fernandez, Marta Montero-Feijoo, Ines Solís-Muñiz, Alvaro Lassaletta

Abstract readCase Reports
In one paragraph

Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Serafin Castellano-DamasoPediatric Neuro-Oncology Unit, Oncology Department. Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Felisa Vazquez-GomezPediatric Neuro-Oncology Unit, Oncology Department. Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Marta Perez-SomarribaPediatric Neuro-Oncology Unit, Oncology Department. Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Mercedes Muñoz-FernandezRadiation Oncology Department, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Marta Montero-FeijooRadiation Oncology Department, Proton Center. Hospital Universitario Quironsalud, Pozuelo de Alarcón, Spain.
Ines Solís-MuñizRadiology Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.
Alvaro LassalettaPediatric Neuro-Oncology Unit, Oncology Department. Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiotherapy for low-grade gliomas (LGG) in neurofibromatosis type 1 (NF1) is normally avoided, since these children are at an elevated risk of developing severe sequelae. NF1 patients are more predisposed to developing radiation-induced malignancies, as well as vasculopathy. However, radiotherapy may help achieve tumor control in patients with life-threatening complications or a long history of relapse. Here we present two NF1 patients in whom radiotherapy managed to achieve full control of the disease without side effects, sparing those patients from needing further therapies. Literature regarding this aspect is also reviewed.

Indexed as

case reportlow-grade gliomasneurofibromatosis 1pediatricradiotherapy

Identifiers

PMID41959909
PMCPMC13056822

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.