ArticleBioinformation2026
A retrospective analysis of interobserver variability in 356 cases over a period 10 years: Celiac disease.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Celiac disease (CD) is an immune-mediated enteropathy in which dietary gluten triggers a T-cell-driven inflammatory injury of the small-intestinal mucosa in genetically predisposed individuals. Therefore, it is of interest to compare the distribution of the diagnostic categories and the interobserver variation of the Modified Marsh-Oberhuber and Corazza-Villanacci histopathological categories in biopsy-proven celiac disease samples of 356 cases collected in 10 years. All duodenal biopsies were reviewed by two independent pathologists who scored it twice with each of the two systems; Cohen concordance was used as a measure of interobserver agreement. Majority of initial diagnoses were compressed in Marsh III subtypes and recategorization showed significant discordance of Marsh (iii) a to (iii) c, which represents little reproducibility. By contrast, Corazza-Villanacci produced majority of Grade B1 tasks with maximal consensus among pathologists, which was highly reproducible and did not compromise clinically valuable stratification. The results argue in favor of the straightforward implementation of the streamlined Corazza-Villanacci system in Indian high throughput settings to increase the consistency of the diagnoses and standardize patient care.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.