ArticleRMD open2026
Spinal mobility and functional limitations in patients with diffuse idiopathic skeletal hyperostosis compared to healthy controls and patients with axial spondyloarthritis.
Article in RMD open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiffuse idiopathic skeletal hyperostosis (DISH) is characterised by ossification of the spine including the anterior longitudinal ligament. While often still considered a pure radiographic finding, recent evidence suggests relevant impairments in physical functioning.
objectiveTo evaluate spinal mobility and functional limitations in DISH compared with radiographic (r-) and non-radiographic (nr-) axial spondyloarthritis (axSpA) and healthy controls (HCs).
methodsConsecutive patients and HCs were assessed regarding mobility, including the Bath Ankylosing Spondylitis Metrology Index (BASMI), Short Physical Performance Battery (SPPB), Ankylosing Spondylitis Performance-based Index (ASPI), electronic measures of measuring range of motion (ROM) and range of kinematics (ROK) with the Epionics SPINE.
resultsWe examined 50 patients with DISH, 30 patients with axSpA and 20 HCs. Compared with HC, patients with DISH showed significantly worse BASMI (4.6±1.0 vs 2.8±0.6), SPPB (10.2±2.0 vs 11.9±0.4), ASPI (46.5±26.1 s vs 20.3±5.3) and broad restrictions across ROM and ROK measures (all p<0.001). Compared with axSpA, BASMI (4.6±1 vs 5.1±1.9; p=0.13), SPPB (10.2±2.0 vs 9.5±1.3; p=0.08) and ASPI (46.5±26.1 vs 47.4±23.9; p=0.91) were comparable, but profiles differed: patients with DISH performed better in rotation to both sides and hip-related measures. Age-adjusted analyses confirmed similar group differences independent of age.
conclusionDISH is associated with substantial impairments in spinal mobility and physical performance compared with HC. While limitations were comparable to axSpA, the restriction pattern differed, with DISH showing less deficits in rotational movement. These findings highlight that DISH is not merely a radiographic condition but patients experience significant impairments of mobility, similar to axSpA.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.