Evidence map›Paper›PMID 41964102›Full record

ReviewInflammation and regeneration2026

Emerging roles of microRNAs and other non-coding transcriptome in muscular dystrophies.

Farah Gamal Abdelrehim, Zade Sadek, Salma A Fahim, Nada El-Ekiaby, Ahmed Ihab Abdelaziz, Injie Omar Fawzy

Abstract readReview
In one paragraph

Review in Inflammation and regeneration, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farah Gamal Abdelrehim *School of Medicine, Newgiza University, Giza, Egypt.
Zade Sadek *School of Medicine, Newgiza University, Giza, Egypt.
Salma A FahimSchool of Medicine, Newgiza University, Giza, Egypt.
Nada El-EkiabySchool of Medicine, Newgiza University, Giza, Egypt.
Ahmed Ihab AbdelazizSchool of Medicine, Newgiza University, Giza, Egypt.
Injie Omar FawzySchool of Medicine, Newgiza University, Giza, Egypt. injie.fawzy@ngu.edu.eg.

Funding

The Science, Technology & Innovation Funding Authority (STDF) Applied Sciences 46321
6 · The paper itself

Abstract

Muscular dystrophies (MDs) are a set of neuromuscular diseases characterized by progressive muscle weakness and wasting. Their pathophysiology entails several aberrant genetic pathways including the perturbation of microRNA (miRNA) and other non-coding RNA (ncRNA) levels and functions, and the subsequent dysregulation of their downstream targets. In healthy tissue, ncRNAs exert their influence by fine-tuning physiological mechanisms. However, in dystrophic conditions, these ncRNAs become involved in modulation of pathological mechanisms. The main pathomechanism themes that involve ncRNAs and proteins in MD are myogenesis insufficiency, structural instability, destructive pathways, and signaling failure. This review attempts to delineate all the major contributory ncRNAs, particularly miRNAs, as well as their associated proteins involved in disease initiation, maintenance, and outcomes across the spectrum of MD subtypes.

Indexed as

DegenerationInflammationMuscle dystrophyMyogenesisNcRNANeuromuscular diseasesNon-coding transcriptomePost-translational modificationsRegeneration

Identifiers

PMID41964102
PMCPMC13072657

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.