ArticleFuture science OA2026
The potential of plant-derived exosome-like nanovesicles from
Article in Future science OA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Article
- Plant-derived exosome-like nanovesicles as programmable bio-organic excipients: a next-generation platform for precision and immuno-silent drug delivery.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThis study aimed to isolate plant-derived exosome-like nanovesicles from MATERIALS &
methodsCA-PDENs were isolated via differential centrifugation and polyethylene glycol (PEG) precipitation, then characterized physically and proteomically Anti-inflammatory effects were assessed in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages. Anti-Photoaging potential was evaluated in ultraviolet B (UVB)-induced 1BR3 fibroblasts. Antibacterial activity against
resultsCA-PDENs are homogenous, spherical vesicles containing metabolite biosynthesis enzymes. They showed no cytotoxicity and were efficiently internalized. Functionally, CA-PDENs significantly suppressed nitric oxide production, indicating pronounced early-phase anti-inflammatory activity, while CD80, CD206, and interleukin-6 (IL-6) modulation showed consistent but non-significant trends. In fibroblasts, CA-PDENs exhibited strong antioxidant activity, reduced intracellular reactive oxygen species (ROS), attenuated collagen degradation, and enhanced wound closure. Moderate antibacterial activity was also observed.
conclusionsCA-PDENs possess robust anti-inflammatory and photoprotective properties, supporting their potential as multifunctional nanocosmetic ingredients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.