ArticlePlant signaling & behavior2026
COP1 regulates the abundance and stability of the Arabidopsis retromer protein AtVPS29 via the proteasome pathway.
Article in Plant signaling & behavior, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Vacuolar protein sorting 29 (VPS29) is a pivotal component of the retromer complex, which plays a central role in endosomal trafficking. Numerous studies have investigated its functions in various eukaryotic systems; however, research in plants is still at an early stage. Moreover, the mechanisms controlling its abundance and stability remain largely unknown. In this study, we elucidated the role of constitutive photomorphogenic 1 (COP1) in regulating the abundance of Arabidopsis VPS29 (AtVPS29), a component of the trimeric retromer complex. Degradation of AtVPS29 is delayed by treatment with the proteasome inhibitor MG132, resulting in the accumulation of ubiquitinated AtVPS29 in MG132-treated plants. The AtVPS29 level is higher in
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