Evidence map›Paper›PMID 41964609›Full record

ArticleJournal of veterinary internal medicine2026

Effect of echocardiographic imaging view and methods on left ventricular wall-thickness measurements in normal cats and cats with hypertrophic cardiomyopathy.

Giovanni Grosso, Karsten Eckhard Schober

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Article in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Giovanni GrossoDepartment of Veterinary Sciences, University of Pisa, Pisa, Italy.
Karsten Eckhard SchoberDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEchocardiographic measurements of left ventricular free wall (LVFW) and interventricular septum (IVS) thickness are essential for diagnosing hypertrophic cardiomyopathy (HCM). HYPOTHESIS/

objectivesTo evaluate agreement between different imaging views and modes for assessing LV wall thickness in cats. We hypothesized that there is clinically relevant bias between methods, and that results cannot be used interchangeably. ANIMALS: Two-hundred eighty cats; 140 controls and 140 with subclinical HCM.

methodsRetrospective, single-center, and cross-sectional study. End-diastolic IVS and LVFW thickness was evaluated by 2-dimensional (2D) and time-motion mode (M-mode) echocardiography, from right parasternal long-axis (RPLax) and right parasternal short-axis (RPSax) views: method-1 (M1), RPLax using 2D; M2, RPLax using M-mode; M3, RPSax using 2D; and M4, RPSax using M-mode. Using 2D images, the thickest portion of the LV wall was measured. Methods were compared using repeated measurement ANOVA on ranks and the Bland-Altman method with bias and 95% limits of agreement (95% LOA).

resultsIn controls, IVS thickness was not different among the 4 methods (P = .67; bias 0.04-0.10 mm, 95% LOA -1.09 to 1.28 mm); whereas LVFW thickness was (P < .001) using M-mode compared to 2D (bias 0.22-0.30 mm; 95% LOA -0.81 to 1.25 mm). In HCM cats, thickness of the IVS (bias -1.07 to -1.13 mm; 95% LOA -3.05 to 0.84 mm) and LVFW (bias 0.22 to -.27 mm; 95% LOA -2.09 to 2.03 mm) was different among methods (P < .001). CONCLUSIONS AND CLINICAL IMPORTANCE: Two-dimensional and M-mode echocardiographic methods in the assessment of LV wall thickness cannot be used interchangeably, particularly in cats with HCM.

Indexed as

Cardiomyopathy, HypertrophicCat DiseasesEchocardiographyHeart VentriclesAnimalsCatsCross-Sectional StudiesFemaleMaleRetrospective Studies2D transthoracic echocardiographyfeline cardiologyHCMinterventricular septumleft ventricular free wall

Identifiers

PMID41964609
PMCPMC13069883

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.