Evidence map›Paper›PMID 41966995›Full record

ArticleJournal of biological rhythms2026

Athira Theyyassanchery Mani, Vivian Backs, Christian Werner, Charlotte Helfrich-Förster, Thomas Raabe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biological rhythms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Athira Theyyassanchery ManiMolecular Genetics, Biocenter, University of Würzburg, Würzburg, Germany.
Vivian BacksMolecular Genetics, Biocenter, University of Würzburg, Würzburg, Germany.
Christian WernerBiotechnology and Biophysics, Biocenter, University of Würzburg, Würzburg, Germany.
Charlotte Helfrich-FörsterNeurobiology and Genetics, Biocenter, University of Würzburg, Würzburg, Germany.ORCID 0000-0002-0859-9092
Thomas RaabeMolecular Genetics, Biocenter, University of Würzburg, Würzburg, Germany.ORCID 0000-0001-9734-4464

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian neuronal plasticity describes daily recurring changes at the level of neuronal morphology, connectivity and synaptic processes. Disturbance of these plastic changes could result in inflexibility of an organism to adapt behavior to changing environmental cues. The mitogen activated protein kinases (MAPK)/ERK signaling pathway is involved both in circadian processes and neuronal plasticity. Ribosomal S6 kinases (RSK) act as downstream mediators of ERK signaling with apparently pleiotropic-but sometimes poorly understood- functions in the nervous system. This is illustrated by some major gaps in our understanding of the pathophysiological processes caused by RSK2 mutations in humans that lead to intellectual disabilities. Previous studies described the role of

Indexed as

Behavior, AnimalCircadian RhythmDrosophilaDrosophila melanogasterDrosophila ProteinsNeuronal PlasticityNeuronsRibosomal Protein S6 KinasesRibosomal Protein S6 Kinases, 70-kDaAnimalsMutationRibosomal Protein S6 Kinases, 90-kDaDrosophila ProteinsRibosomal Protein S6 KinasesRibosomal Protein S6 Kinases, 70-kDaRibosomal Protein S6 Kinases, 90-kDaadaptationcircadian rhythmclock neuronsDrosophilastructural plasticity

Identifiers

PMID41966995
PMCPMC13342480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.