Evidence mapPaperPMID 41968217Full record

ArticleObesity surgery2026

The Weight of the Matter: Preoperative Metabolic Dysfunction-Associated Steatotic Liver Disease and its Limited Impact on Bariatric Outcomes.

Motahare Moosavi, Tooraj Zandbaf, Keivan Kalali, Hanie Gholami, Amin Dalili, Mohammad Javad Ghamari

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Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

6 authors.

Motahare MoosaviStudent Research Committee, MMS.C., Islamic Azad University, Mashhad, Mashhad, Iran, Islamic Republic of.
Tooraj ZandbafDepartment of General Surgery, MMS.C, Islamic Azad University, Mashhad, Mashhad, Iran, Islamic Republic of. tooraj.zandbaf@gmail.com.
Keivan KalaliStudent Research Committee, MMS.C., Islamic Azad University, Mashhad, Mashhad, Iran, Islamic Republic of.
Hanie GholamiStudent Research Committee, MMS.C., Islamic Azad University, Mashhad, Mashhad, Iran, Islamic Republic of.
Amin DaliliSurgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, Islamic Republic of.
Mohammad Javad GhamariDepartment of General Surgery, MMS.C, Islamic Azad University, Mashhad, Mashhad, Iran, Islamic Republic of. mohammad.j.ghamari@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMetabolically-dysfunction-associated steatotic liver disease (MASLD) is a prevalent comorbidity of obesity, with metabolic bariatric surgery (MBS) suggested as the only definitive treatment. Concerns have been raised about altered weight loss patterns in patients with MASLD undergoing MBS; therefore, we aimed to evaluate the influence of MASLD on postoperative weight loss patterns after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG).

methodData from 347 patients who underwent MBS between 2020 and 2024 were retrospectively reviewed. Patients were followed at 1, 6, and 12 months postoperatively. Weight, body mass index (BMI), excess weight loss (EWL), and total weight loss (TWL) were compared both by the presence of MASLD and by the different ultrasound-determined grades of MASLD.

resultAfter 12 months postoperatively, weight and BMI were lower in the no MASLD groups than in the MASLD group (74.61 vs. 77.04 for weight and 28.49 vs. 29.21 for BMI in the RYGB group, and 71.03 vs. 74.92 for weight and 27.41 vs. 29.05 for BMI in the SG group). However, after adjusting for age, sex, history of diabetes, baseline BMI, and baseline weight, as well as the alimentary and biliopancreatic limbs in RYGB, multivariate analysis of repeated measures ANOVA revealed that the overall pattern of the MASLD group was statistically similar to that of the no MASLD group.

conclusionPreoperative MASLD does not appear to influence weight loss outcomes after RYGB or SG significantly. Larger prospective studies are required to clarify the predictive value of MASLD on postoperative weight loss patterns after MBS.

Indexed as

Bariatric SurgeryFatty LiverGastrectomyGastric BypassObesity, MorbidWeight LossAdultBody Mass IndexFemaleHumansMaleMiddle AgedPreoperative PeriodRetrospective StudiesTreatment OutcomeMASLDMetabolic and Bariatric SurgeryRoux-en-Y Gastric BypassSleeve GastrectomyWeight Loss

Identifiers

PMID41968217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.