Evidence map›Paper›PMID 41969751›Full record

ArticleBiomaterial investigations in dentistry2026

Antibiofilm and antibacterial effects of

Sherif ELsayed, Khaled El-Adl, Doaa M Sadony, Haidy A Gad, Abdullah Yousef, Ahmed A Radwan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomaterial investigations in dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sherif ELsayedBiomaterials Department, Faculty of Dentistry, Galala University, Suez, Egypt.
Khaled El-AdlChemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt.
Doaa M SadonyRestorative and Dental Materials Department, National Research Centre, Dokki, Giza, Egypt.
Haidy A GadDepartment of Pharmacognosy, Ain Shams University, Cairo, Egypt.
Abdullah YousefBasic & Medical Sciences Department, Faculty of Dentistry, Al-Ryada University for Science and Technology. Sadat City, Menoufia, Egypt.
Ahmed A RadwanGenetics and Cytology Department, National Research Centre (NRC), Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the antibiofilm and antibacterial properties of Methods: Chemical analysis of aqueous extract powder of Results: GC-MS revealed high concentration of long chain FAs (linoleic, oleic and palmitic acids). NSE and CHX groups showed significantly the highest red (dead) RF. NSE caused the highest reduction in biofilm thickness. NSE and CHX presented the minimum absorbance in CV assay. MD predicted a high binding affinity between FAs ligands and MurA receptors (Arg371, Arg331, Asn23, Lys22), with maximum affinity to linoleic acid (-98.07 kcal/mol). Conclusion: NSE showed antibacterial effect against

Indexed as

CLSMfatty acidsmolecular dockingMurA enzymeNigella sativaoral biofilmStreptococcus mutans

Identifiers

PMID41969751
PMCPMC13062899

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.