ReviewFrontiers in pharmacology2025
The pharmacological effects and therapeutic potential of flavonoids in digestive diseases.
Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Casticin Alleviates Acetaminophen-Induced Acute Liver Injury by Modulating the TLR4/MyD88/TRAF6/NF-κB Signaling Pathway.Pharmaceuticals (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Digestive system diseases remain highly prevalent globally and constitute a major cause of mortality and disability. They not only severely compromise individual health but also result in massive consumption of medical resources, exacerbating socioeconomic burdens, thus emerging as a critical global public health challenge requiring resolution. In the prevention and treatment of digestive system diseases, flavonoids exhibit therapeutic potential through multiple targets and pathways. Methods: This review retrieved and summarized relevant literature on flavonoids for the treatment of digestive diseases published between 2000 and 2025 in databases including PubMed, Web of Science, Excerpta Medica Database, Wiley Online Library, SpringerLink, Nature Publishing Group, American Chemical Society, Elsevier, and Royal Society of Chemistry. Keywords (flavonoids, digestive diseases, pharmacological effects, anti-inflammation, antioxidation) were used for searching. During screening, priority was given to flavonoids directly related to the pathogenesis or intervention effects of digestive diseases, with study types covering reviews, clinical trials, randomized controlled trials, Results: Flavonoids can prevent and treat digestive system diseases Conclusion: Although flavonoids exhibit significant pharmacological effects and favorable safety profiles in the prevention and treatment of digestive diseases, laying a foundation for the development of new drugs, they still face numerous challenges in clinical application. In the future, it is necessary to further conduct high-quality clinical studies, deepen research on the molecular mechanisms of their actions, and promote their translation from basic research to clinical practice.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.