ArticleHealth science reports2026
Choroidal Vascularity Index in Schizophrenia Compared to Healthy Subjects: A Cross-Sectional Study.
Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Background and Aims: This study aims to evaluate choroidal vascular architecture in patients with schizophrenia compared to healthy individuals. Methods: This cross-sectional study was conducted between 2019 and 2021. In total, 22 hospitalized patients with documented instances of schizophrenia and 22 healthy subjects were included. Demographic, clinical ophthalmic, psychiatric, and enhanced-depth imaging optical coherence tomography (EDI-OCT) data were gathered. The choroidal luminal area (LA), total choroidal area (TCA), and choroidal thickness (CT) were calculated using the ImageJ software. The choroidal vascularity index (CVI) was calculated as the ratio of LA to TCA. Results: The mean ± standard deviation (SD) of the LA was 0.301 ± 0.03 mm Conclusion: Increased CVI supports the hypothesis of microvascular dysfunction in schizophrenia. However, the precise mechanism and pathogenesis of microvascular changes in schizophrenia are unclear.
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