ArticleJournal of oral microbiology2026
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Oral pathogens play a significant role in the pathogenesis of Alzheimer's disease (AD) via the oral-brain axis and oral-gut-brain axis. However, how Objective: To investigate the effects of Design: Sixty C57BL/6 mice were divided into two cohorts and infected with Results: Gingival injection resulted in cognitive impairment, neuronal loss in the hippocampal CA1/CA3 regions (p < 0.05), overactivation of microglia and increased expression of proinflammatory cytokines (IL-1β and TNF-α, p < 0.05) and NF-κB in hippocampus (p < 0.05). Similar cognitive impairments and cerebral changes were noted after oral gavaging. Additionally, oral gavage induced gut microbiota dysbiosis, intestinal inflammation and decreased expression of tight junction in intestinal barrier and blood-brain barrier (ZO-1, Occludin, Claudin-1 and Claudin-5, p < 0.05). Furthermore, AD patients exhibited oral microbiota dysbiosis, with a higher relative abundance of Conclusion:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.