Evidence map›Paper›PMID 41971469›Full record

ArticleCase reports in obstetrics and gynecology2026

Fertility-Sparing Management of HPV-Associated FIGO IB1 Mucinous Cervical Adenocarcinoma With Signet-Ring Cell Features: A Case Report.

Luiz Felipe Lessa Ortiz, Amanda Lino de Faria Lessa, Rafael Dyer Rodrigues de Moraes, Renan Ribeiro E Ribeiro, Henrique Cunha Vieira, Bárbara Bomfim Muniz Moraes, Roney César Signorini Filho, Giorgio Bogani

Abstract read
In one paragraph

Article in Case reports in obstetrics and gynecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luiz Felipe Lessa OrtizGAVVA Clínica-Medicina Reprodutiva e Oncofertilidade, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7268-8324
Amanda Lino de Faria LessaGAVVA Clínica-Medicina Reprodutiva e Oncofertilidade, São Paulo, Brazil.
Rafael Dyer Rodrigues de MoraesCICAP-Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.
Renan Ribeiro E RibeiroCICAP-Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-2580-7655
Henrique Cunha VieiraGAVVA Clínica-Medicina Reprodutiva e Oncofertilidade, São Paulo, Brazil.
Bárbara Bomfim Muniz MoraesGAVVA Clínica-Medicina Reprodutiva e Oncofertilidade, São Paulo, Brazil.
Roney César Signorini FilhoHospital da Mulher-Pérola Byington, São Paulo, Brazil.
Giorgio BoganiIRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fertility-sparing surgery is an increasingly accepted option in carefully selected patients with early-stage cervical cancer. Radical vaginal trachelectomy combined with sentinel lymph node (SLN) mapping offers oncologic safety while preserving reproductive potential. Case: A 29-year-old nulliparous woman with FIGO stage IB1 poorly differentiated HPV-associated mucinous cervical adenocarcinoma with signet-ring cell features underwent radical vaginal trachelectomy and bilateral laparoscopic SLN mapping using indocyanine green (ICG). No nodal metastases were identified. Surgical margins were negative, and an abdominal cervical cerclage was placed. At 24 months of follow-up, the patient remains disease-free and is receiving counseling regarding assisted reproductive technologies. Conclusion: Fertility-preserving surgery may be safely performed in selected early-stage cervical cancer patients when combined with appropriate surgical staging and close follow-up. This case adds to the limited literature regarding the conservative management of high-grade mucinous adenocarcinomas with signet-ring cell morphology.

Indexed as

cervical cancerfertility preservationmucinous adenocarcinomaradical trachelectomysentinel lymph nodesignet-ring cells

Identifiers

PMID41971469
PMCPMC13062658

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.