ArticleChinese herbal medicines2026
Novel step-by-step strategy for evaluating treatment of traditional Chinese medicine injections for community-acquired pneumonia in adults.
Article in Chinese herbal medicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Community-acquired pneumonia (CAP) is a leading cause of death from infectious diseases in adults worldwide. Traditional Chinese medicine injections (TCMIs) are often used as complementary therapies. This study aimed to evaluate the efficacy and safety of TCMIs for the treatment of CAP. Methods: A step-by-step strategy was first designed including data collection, systematic review, Bayesian network Results: A total of 35 RCTs involving 4 291 participants were included. For clinical effectiveness rate, the Reduning Injection (RDN) combined with Western medicine (WM) was the most likely to be the best treatment (SUCRA = 0.919). And the top three TCMIs interventions were RDN + WM, Xiyanping Injection (XYP) + WM, Tanreqing injection (TRQ) + WM. For defervescence time, disappearance time of cough, and the disappearance time of lung rales, the XYP with WM was probably the best treatment (SUCRA = 0.822, 0.838, 0.816). Moreover, adverse drug reactions have been reported in 14 RCTs. Conclusion: The TCMIs can effectively relieve clinical symptoms and improve clinical efficiency than that of WM alone for adults with non-severe CAP. Step-by-step results firstly indicated that XYP with WM was superior treatment regimen to reduce defervescence time, disappearance time of cough and disappearance time of lung rales. For safety, the mild adverse drug reactions occurred during the entire course of therapy and were self-limiting, further confirming the favorable safety profile of the TCMIs.
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