Evidence map›Paper›PMID 41972731›Full record

ArticleCells2026

FGF2 Deficiency Modulates Early Microglial Responses Without Affecting Photoreceptor Survival in a Retinitis Pigmentosa Mouse Model.

Felia C Haffelder, Nundehui Díaz-Lezama, Zeynep Okutan, Claudia Grothe, Susanne F Koch

Abstract read
In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Felia C HaffelderDepartment of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0009-0002-0916-1671
Nundehui Díaz-LezamaDepartment of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0000-0001-9025-6090
Zeynep OkutanDepartment of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.ORCID 0009-0003-3440-1312
Claudia GrotheInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.
Susanne F KochDepartment of Pharmacy, Center for Drug Research, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

Funding

Bayerische Forschungsstiftung 1597-23German Research Foundation KO 5719/1-1German Research Foundation KO 5719/3-1
6 · The paper itself

Abstract

Fibroblast growth factor 2 (FGF2) is expressed in retinal Müller glia cells, and its expression increases in response to photoreceptor degeneration. To investigate the physiological relevance of FGF2, we analyzed retinal morphology and cellular responses in

Indexed as

Fibroblast Growth Factor 2MicrogliaPhotoreceptor Cells, VertebrateRetinitis PigmentosaAnimalsCell SurvivalCyclic Nucleotide Phosphodiesterases, Type 6Disease Models, AnimalMiceMice, Inbred C57BLMice, KnockoutRetinal DegenerationRetinal Pigment EpitheliumCyclic Nucleotide Phosphodiesterases, Type 6Fibroblast Growth Factor 2fibroblast growth factor 2 (FGF2)microglianeuroinflammationphotoreceptor degenerationretinal pigment epithelium (RPE)retinitis pigmentosa

Identifiers

PMID41972731
PMCPMC13073567

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.