Cellular Processes and Forces Shaping the Embryo: Lessons from

Michel Labouesse, Teresa Ferraro, Flora Llense, Jonathon Heier, Zoe Tesone, Jeff Hardin

Abstract readReview

In one paragraph

Review in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michel LabouesseDevelopment, Adaptation and Ageing (Dev2A)-Institut de Biologie Paris Seine, Sorbonne Université, 7-9 Quai Saint-Bernard, 75005 Paris, France.

Teresa FerraroDevelopment, Adaptation and Ageing (Dev2A)-Institut de Biologie Paris Seine, Sorbonne Université, 7-9 Quai Saint-Bernard, 75005 Paris, France.

Flora LlenseDevelopment, Adaptation and Ageing (Dev2A)-Institut de Biologie Paris Seine, Sorbonne Université, 7-9 Quai Saint-Bernard, 75005 Paris, France.ORCID 0009-0000-3043-9397

Jonathon HeierDepartment of Integrative Biology, University of Wisconsin-Madison, 1117 W. Johnson St. Madison, Madison, WI 53706, USA.

Zoe TesoneCellular and Molecular Biology Program, University of Wisconsin-Madison, 1117 W. Johnson St. Madison, Madison, WI 53706, USA.

Jeff HardinDepartment of Integrative Biology, University of Wisconsin-Madison, 1117 W. Johnson St. Madison, Madison, WI 53706, USA.ORCID 0000-0001-7399-6580

Funding

Regulation of dynamic actin networks during epithelial morphogenesisR35GM145312 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Jeffrey D Hardin · 2022 to 2026

$3.0M

Agence Nationale de la Recherche ANR-18-CE13-0008-01Agence Nationale de la Recherche ANR-22-CE13-0037European Research Council 294744National Institute of Health R35GM145312NIGMS NIH HHS R35 GM145312

6 · The paper itself

Abstract

Embryo and organ shapes emerge from the interplay between genetic programs and physical forces. In recent years, there has been a growing appreciation of the role of mechanical forces in morphogenesis. Here, we review how the integration of advanced genetic approaches with high-resolution imaging, biophysics, and modeling has begun to yield new insights into

Indexed as

Caenorhabditis elegansEmbryo, NonmammalianAnimalsBody PatterningMechanotransduction, CellularMorphogenesisadherens junctionaxis extensionC. eleganscytoskeletondorsal intercalationhemidesmosomemechanotransductionrosetteventral enclosureα-catenin

Identifiers

PMID41972734

DOI10.3390/cells15070645

PMCPMC13072950

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.