Evidence mapPaperPMID 41973294Full record

ArticleAnnals of surgical oncology2026

Consensus Guidelines on Perioperative Care in Primary Retroperitoneal Sarcoma Surgery.

Pablo Lozano Lominchar, Óscar Díaz-Cambronero, Paula Muñoz-Muñoz, Alba Fernández-Candela, Pilar Hernández-Sánchez, Nuria Javaloyes, Vicente Olivares, Catarina Costa Rodrigues, Isabel Prieto Nieto, Daniel Díaz-Gómez and 20 more

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Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Pablo Lozano LomincharDepartment of General Surgery and Surgical Oncology, Hospital General Universitario Gregorio Maranon. IISGM, Madrid, Spain.
Óscar Díaz-CambroneroDepartment of Anesthesiology, Hospital Universitario La Fe, Valencia, Spain.
Paula Muñoz-MuñozDepartment of General Surgery and Surgical Oncology, Hospital Quironsalud Torrevieja, Alicante, Spain.
Alba Fernández-CandelaDepartment of General Surgery and Surgical Oncology, Hospital Quironsalud Torrevieja, Alicante, Spain.
Pilar Hernández-SánchezNutrition Unit, Oncological Platform, Hospital QuirónSalud Torrevieja, Alicante, Spain.
Nuria JavaloyesDepartment of Psyco-Oncology, Hospital Quironsalud Torrevieja, Alicante, Spain.
Vicente OlivaresDepartment of General Surgery, Hospital Universitario Virgen de La Arrixaca, Murcia, Spain.
Catarina Costa RodriguesDepartment of Anesthesiology, Instituto Portuguese of Oncology (IPO), Francisco Gentil de Lisboa, Lisbon, Portugal.
Isabel Prieto NietoDepartment of General Surgery, Hospital Universitario La Paz, Madrid, Spain.
Daniel Díaz-GómezDepartment of General Surgery, Hospital Universitario Virgen del Rocío, Sevilla, Spain.
Cristina Ballester IbañezDepartment of General and Digestive Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Pedro PintoDepartment of Anesthesiology, Instituto Portuguese of Oncology (IPO), Francisco Gentil de Lisboa, Lisbon, Portugal.
Patricia Marrero-MarreroDepartment of General and Digestive Surgery. Section of Mesenchymal Tumors and Sarcomas, Hospital Universitario de Canarias, Tenerife, España.
Mercedes LópezDepartment of Anesthesiology, Hospital Universitario La Paz, Madrid, Spain.
Irene VallejoDepartment of Anesthesiology, Hospital Universitario La Paz, Madrid, Spain.
Mercedes Campos SanzDepartment of Anesthesiology, Hospital Universitario La Paz, Madrid, Spain.
Flavio VideiraDepartment of Surgical Oncology, Instituto Portuguese of Oncology (IPO), Porto, Portugal.
Pedro MartinsDepartment of Surgical Oncology, Instituto Portuguese of Oncology (IPO), Porto, Portugal.
Paco OrbisDepartment of General and Digestive Surgery, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Alicia RubioDepartment of Anesthesiology, Hospital Universitario La Paz, Madrid, Spain.
Sonia Otalora ValderramaDepartment of Internal Medicine, Advanced Unit for Venous Thromboembolic Disease, Hospital Universitario Virgen de La Arrixaca, Murcia, Spain.
Francisco BermúdezDepartment of Anesthesiology, Hospital Universitario La Paz, Madrid, Spain.
Rosa ÁlvarezDepartment of Medical Oncology, Hospital General Universitario Gregorio Maranon, Madrid, Spain.
Christina L RolandDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Heather LyuDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Callisia N ClarkeDivision of Surgical Oncology, Medical College of Wisconsin, Milwauke, USA.
Cristobal Muñoz-CasaresDepartment of General Surgery and Surgical Oncology, Hospital San Juan de Dios, Córdoba, Spain.
José Manuel AsencioDepartment of General Surgery and Surgical Oncology, Hospital General Universitario Gregorio Maranon. IISGM, Madrid, Spain. jmasencio@gmail.com.
Hugo VasquesDepartment of Surgical Oncology, Instituo Português de Oncologia (IPO), Francisco Gentil de Lisboa, Lisbon, Portugal.
Spanish Society of Surgeons and the Portuguese Sarcoma Group (Society of Surgeons)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrimary retroperitoneal sarcomas (RPS) represent a rare group of malignancies requiring aggressive surgical management. While Enhanced Recovery After Surgery (ERAS) protocols have improved perioperative outcomes across many surgical disciplines, disease-specific guidance for RPS is lacking. This consensus aims to standardize perioperative care in primary RPS surgery on the basis of current evidence and expert opinion.

methodsA multidisciplinary panel of experts was convened under the auspices of the Spanish Society of Surgeons and the Portuguese Sarcoma Group. Between January and June 2025, a modified Delphi process was conducted, incorporating systematic literature review, subgroup synthesis, and four structured voting rounds. The strength of each recommendation was graded using the GRADE framework, and consensus was defined as ≥80% agreement among participants.

resultsA total of 42 recommendations were proposed, addressing preoperative (e.g., anemia correction, smoking cessation, nutritional optimization), intraoperative (e.g., antimicrobial prophylaxis, goal-directed fluid therapy, multimodal analgesia), and postoperative care (e.g., ileus prevention, early feeding, opioid-sparing strategies, mobilization). In total, 33 recommendations reached consensus-17 with weak consensus and 16 with strong consensus-while 9 did not meet the predefined threshold. Most recommendations were supported by indirect evidence from major abdominal and oncologic surgery literature.

conclusionsThese are the first consensus-based, multidisciplinary perioperative care guidelines tailored to primary RPS surgery. They aim to harmonize clinical practice, reduce variation, and improve surgical and recovery outcomes in high-risk patients. Prospective validation and international collaboration are encouraged to further refine and implement these recommendations.

Indexed as

Perioperative CarePractice Guidelines as TopicRetroperitoneal NeoplasmsSarcomaConsensusHumansConsensus guidelinesEnhanced recoveryERASPerioperative careRetroperitoneal sarcomaSurgical oncology

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.