Evidence mapPaperPMID 41976211Full record

ReviewMolecules (Basel, Switzerland)2026

Engineering Strategies of Colloidal Drug Delivery Systems, a Rising Star in Ocular Neovascular Diseases.

Yueping Bai, Lu Liu, Cui Li, Yiping Ma, Pai Liu, Shuo Wang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yueping BaiTianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin 300020, China.
Lu LiuTianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin 300020, China.
Cui LiTianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin 300020, China.
Yiping MaTianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin 300020, China.
Pai LiuState Key Laboratory of Advanced Separation Membrane Materials, School of Materials Science and Engineering, Tiangong University, Tianjin 300387, China.ORCID 0000-0002-9003-3652
Shuo WangTianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Hospital, Tianjin 300020, China.ORCID 0000-0002-4224-3807

Funding

Hebei Natural Science Foundation B2024110008, B2025110067Nankai University Optometry Science Research Institute Fund NKSGZ202512the research funding provided by the Cangzhou Institute of Tiangong University TGCYY-F-0305Tianjin Health Commission Traditional Chinese and Western Medicine Integrated Scientific Research Project 2025179Tianjin Key Medical Discipline Construction Project TJYXZDXK-3-004A-3Tianjin Ophthalmic Pharmaceutical Research Project YKYXZ01, YKYXZ02
6 · The paper itself

Abstract

Ocular neovascular diseases represent a major cause of irreversible vision loss worldwide, while the complex ocular barrier system significantly limits the efficacy of conventional treatment approaches. In this context, colloidal drug delivery systems (CDDSs) have emerged as an innovative nanomedicine strategy that demonstrates remarkable advantages in enhancing ocular drug bioavailability and treatment precision through the integration of sustained release, active targeting, and stimulus-responsive functional modules. This review systematically summarizes recent research advances in CDDSs for treating ocular neovascular diseases, with a particular focus on design strategies and mechanisms for overcoming physiological barriers and achieving lesion-specific drug delivery. Furthermore, it provides in-depth analysis of key challenges in current clinical translation. With ongoing technological advancements, CDDSs are expected to offer breakthrough solutions for treating ocular neovascular diseases, ultimately leading to significant improvements in patients' visual prognosis and quality of life.

Indexed as

Choroidal NeovascularizationDrug Delivery SystemsAnimalsColloidsHumansNanomedicineColloidscolloidal drug delivery systemsocular neovascular diseasesocular physiological barriersstimulus-responsive nanomedicine

Identifiers

PMID41976211
PMCPMC13074467

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.