Evidence map›Paper›PMID 41976249›Full record

ReviewMolecules (Basel, Switzerland)2026

Bioprospecting Underutilized Plant By-Products for Antioxidant Natural Extracts: A Review.

Jesús Morales-Jiménez, Rosy G Cruz-Monterrosa, Monzerrat Rosas Espejel, Ildefonso Guerrero-Encinas, Javier N González-González, Luis Quihui-Cota, Jorge L Mejía-Méndez, Alejandra Miranda-Carrazco, José E Aguilar-Toalá

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jesús Morales-JiménezDepartamento de Ciencias Ambientales, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Lerma. Av. de las Garzas 10. Col. El Panteón, Lerma de Villada 52005, Estado de México, Mexico.
Rosy G Cruz-MonterrosaDepartamento de Ciencias de la Alimentación, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Lerma. Av. de las Garzas 10. Col. El Panteón, Lerma de Villada 52005, Estado de México, Mexico.
Monzerrat Rosas EspejelDepartamento de Ciencias de la Alimentación, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Lerma. Av. de las Garzas 10. Col. El Panteón, Lerma de Villada 52005, Estado de México, Mexico.
Ildefonso Guerrero-EncinasCentro de Investigación en Alimentación y Desarrollo, A.C. (CIAD A.C.), Carretera Gustavo Enrique Astiazarán Rosas No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.ORCID 0000-0002-5617-9244
Javier N González-GonzálezCentro de Investigación en Alimentación y Desarrollo, A.C. (CIAD A.C.), Carretera Gustavo Enrique Astiazarán Rosas No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Luis Quihui-CotaCentro de Investigación en Alimentación y Desarrollo, A.C. (CIAD A.C.), Carretera Gustavo Enrique Astiazarán Rosas No. 46, Col. La Victoria, Hermosillo 83304, Sonora, Mexico.
Jorge L Mejía-MéndezTecnológico de Monterrey, Escuela de Ingeniería y Ciencias, Epigmenio González 500, San Pablo, Santiago de Querétaro 76130, Querétaro, Mexico.ORCID 0000-0001-8252-5211
Alejandra Miranda-CarrazcoDepartamento de Ciencias Ambientales, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Lerma. Av. de las Garzas 10. Col. El Panteón, Lerma de Villada 52005, Estado de México, Mexico.ORCID 0000-0003-3637-5114
José E Aguilar-ToaláDepartamento de Ciencias de la Alimentación, División de Ciencias Biológicas y de la Salud, Universidad Autónoma Metropolitana, Unidad Lerma. Av. de las Garzas 10. Col. El Panteón, Lerma de Villada 52005, Estado de México, Mexico.ORCID 0000-0001-6823-8785

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Underutilized plant by-products are an overlooked source of natural extracts that contain antioxidant bioactive compounds and therapeutic potential. Oxidative stress significantly contributes to the development of various chronic diseases. In this context, natural extracts rich in bioactive compounds derived from underutilized plant by-products emerge as promising options for developing antioxidant-based therapies that target oxidative stress-related molecular pathways involved in the pathogenesis of chronic disease. The valorization of by-products through the recovery of antioxidant-rich extracts is particularly appealing, as non-edible plant parts often contain higher levels of bioactive compounds than their edible counterparts. This review provides a comprehensive overview of antioxidant natural extracts and their major bioactive components, including polyphenols (particularly flavonoids and phenolic acids), terpenoids, alkaloids, and other redox-active compounds.

Indexed as

AntioxidantsBiological ProductsBioprospectingPlant ExtractsPlantsFlavonoidsHumansOxidative StressPolyphenolsAntioxidantsBiological ProductsFlavonoidsPlant ExtractsPolyphenolsby-product valorizationoxidative stresspolyphenols

Identifiers

PMID41976249
PMCPMC13074691

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.