Evidence map›Paper›PMID 41977210›Full record

ArticleInternational journal of molecular sciences2026

Renoprotective Potential of Nateglinide in an Acute Kidney Injury Model.

Senanur Ilıkça, Samet Öz, Güldeniz Şekerci, Aslı Taşlıdere, Suat Tekin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Senanur IlıkçaDepartment of Physiology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey.
Samet ÖzDepartment of Veterinary Medicine, School of Health Services, Osmaniye Korkut Ata University, 80000 Osmaniye, Turkey.
Güldeniz ŞekerciDepartment of Physiology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey.
Aslı TaşlıdereDepartment of Histology and Embryology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey.
Suat TekinDepartment of Physiology, Faculty of Medicine, Inonu University, 44280 Malatya, Turkey.

Funding

Inonu University TSG-2024-3564Inonu University TYL-2024-3761
6 · The paper itself

Abstract

Nateglinide (Nat) is an oral antidiabetic agent of the meglitinide class that has been reported to exert protective effects beyond glycemic control, particularly against oxidative stress and inflammation. Since oxidative stress and inflammation play a key role in the pathogenesis of acute kidney injury (AKI), especially following ischemia/reperfusion (I/R), this study aimed to evaluate the potential renoprotective effects of Nat in a rat model of I/R-induced AKI. Forty male Sprague Dawley rats were randomly divided into four groups (

Indexed as

Acute Kidney InjuryNateglinideReperfusion InjuryAnimalsAntioxidantsBlood Urea NitrogenCatalaseCreatinineDisease Models, AnimalGlutathioneInterleukin-1betaKidneyMaleOxidative StressRatsRats, Sprague-DawleyAntioxidantsCatalaseCreatinineGlutathioneInterleukin-1betaNateglinideSuperoxide DismutaseThiobarbituric Acid Reactive SubstancesTumor Necrosis Factor-alphaacute kidney injuryapoptosisinflammationischemia/reperfusionnateglinideoxidative stress

Identifiers

PMID41977210
PMCPMC13072856

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.