Evidence map›Paper›PMID 41977233›Full record

ArticleInternational journal of molecular sciences2026

Serum Eosinophil Cationic Protein (ECP) as a Biomarker for Distinguishing Pediatric Allergic Airway Diseases.

Xiaolin Chen, Siyu Tan, Qinxue Lu, Ting Liu, Yongmei Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaolin ChenDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0004-0725-5978
Siyu TanDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Qinxue LuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Ting LiuDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.
Yongmei JiangDepartment of Laboratory Medicine, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

Funding

Sichuan University 24H1193
6 · The paper itself

Abstract

This study evaluated serum eosinophil cationic protein (ECP) as a biomarker for pediatric allergic airway diseases. A cross-sectional analysis was performed on children (1-17 years) with allergic asthma (AA, n = 124), allergic rhinitis (AR, n = 74), acute bronchitis (AB, n = 72), and healthy controls (HC, n = 58). Serum ECP, total IgE, eosinophil counts, allergen sensitization, and lung function were measured. Diagnostic performance was assessed using receiver operating characteristic (ROC) curves, and correlations among biomarkers were examined. Compared with HC, serum ECP levels were significantly elevated across all disease groups (AA, AR, and AB), with a particularly marked difference observed between AA and AR patients (

Indexed as

Eosinophil Cationic ProteinRespiratory HypersensitivityAdolescentBiomarkersCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleRespiratory Function TestsBiomarkersEosinophil Cationic Proteinairway allergic diseasesallergic asthmaallergic rhinitisECP

Identifiers

PMID41977233
PMCPMC13073522

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.