Evidence map›Paper›PMID 41977263›Full record

ReviewInternational journal of molecular sciences2026

The Influence of Monosaccharide Composition on the Bioactivity of Medicinal Plant Polysaccharides.

Xinhui Fan, Ke Li, Maohui Yang, Xuemei Qin, Zhenyu Li, Yuguang Du

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Recent advances inFood chemistry: X · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xinhui FanModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.ORCID 0009-0005-2009-0589
Ke LiModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.
Maohui YangModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.
Xuemei QinModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.
Zhenyu LiModern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China.
Yuguang DuState Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100700, China.

Funding

National Natural Science Foundation of China 81872962
6 · The paper itself

Abstract

Polysaccharides are natural polymers that are widely found in medicinal plants. Structurally, they are complex molecules composed of long chains of monosaccharide units linked by glycosidic bonds. Modern pharmacological research shows that the bioactivity of polysaccharides is closely related to their monosaccharide composition. This review summarises the monosaccharide composition of 210 polysaccharides from 72 medicinal plants. They were classified into 10 types through principal component analysis (glucans; homogalacturonan; galactans; arabinogalactans; mannans; glucomannans; arabinans; xylans; fructans; rhamnogalacturonan-I). The relationship between monosaccharide composition and biological activity was further analysed. The results are as follows: glucans make significant contributions to immunomodulation, antioxidant activity, and gut microbiota regulation; galactans are crucial for antioxidant effects, immunomodulation, and gut microbiota regulation; mannans play a key role in immunomodulation, antitumor activity, and neuroprotection; fructans are vital for gut microbiota regulation, immunomodulation, and antioxidant effects; and pectins exhibit notable immunomodulatory, antioxidant, and hypoglycaemic properties. Consequently, developing polysaccharides from medicinal plant resources based on their monosaccharide composition is expected to speed up the search for polysaccharides with high biological activity and provide a theoretical reference for polysaccharide research.

Indexed as

MonosaccharidesPlants, MedicinalPolysaccharidesAnimalsAntioxidantsHumansAntioxidantsMonosaccharidesPolysaccharidesbioactivitymedicinal plant polysaccharidesmonosaccharide composition

Identifiers

PMID41977263
PMCPMC13073622

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.