Evidence mapPaperPMID 41978180Full record

ReviewNutrients2026

The Potential Role of Dietary (Poly)phenols in Cardiometabolic Risk During Menopause: A Narrative Review.

Lorena Sánchez-Martínez, Rocío González-Barrio, María Jesús Periago

Abstract readReview
In one paragraph

Review in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lorena Sánchez-MartínezDepartment of Food Technology, Food Science and Nutrition, University of Murcia, Campus Mare Nostrum, Campus de Espinardo, 30100 Murcia, Spain.ORCID 0000-0001-9167-5510
Rocío González-BarrioDepartment of Food Technology, Food Science and Nutrition, University of Murcia, Campus Mare Nostrum, Campus de Espinardo, 30100 Murcia, Spain.ORCID 0000-0002-6648-5229
María Jesús PeriagoDepartment of Food Technology, Food Science and Nutrition, University of Murcia, Campus Mare Nostrum, Campus de Espinardo, 30100 Murcia, Spain.ORCID 0000-0003-2096-0167

Funding

Fundación Séneca - Agencia de Ciencia y Tecnología de la Región de Murcia 20904/PI/2018
6 · The paper itself

Abstract

Menopause is a pivotal stage in women's life that brings with it multiple physiological changes that significantly increase the risk of cardiometabolic diseases. (Poly)phenols are plant secondary metabolites that present several mechanisms of action that could improve human health, including the regulation of gene expression, the control of lipid metabolism, the maintenance of glucose homeostasis, a reduction in blood pressure, prebiotic effects, and antioxidant and anti-inflammatory activities. This narrative review summarizes current evidence on the main cardiometabolic risk factors associated with menopause (i.e., obesity, dyslipidemia, high blood pressure, and insulin resistance) and examines the potential of dietary strategies focused on (poly)phenol intake to mitigate these alterations. Current evidence suggests that dietary intervention based on (poly)phenol intake could be a great strategy to mitigate cardiometabolic alterations during menopause. Moreover, this review underscores the crucial need to develop personalized nutrition strategies to optimize the effectiveness of (poly)phenol-rich diets for postmenopausal women's health, thereby alleviating the cardiometabolic risk associated with this pivotal stage of women's lives. In addition, this work emphasizes that future research should comprehensively address the key factors involved in the main mechanisms of action of (poly)phenols in promoting health, including (poly)phenol bioavailability, the role of the gut microbiota in the colonic metabolization of these bioactive compounds, and the regulation of gene expression via nutrigenomic effects related to cardiometabolic diseases. This integrative approach will be essential for establishing evidence-based dietary recommendations for (poly)phenol intake during menopause.

Indexed as

Cardiometabolic Risk FactorsCardiovascular DiseasesDietMenopausePolyphenolsFemaleGastrointestinal MicrobiomeHumansPolyphenolsbioactive compoundsblood pressureendothelial cell adhesion biomarkersgut microbiotainflammationinsulin resistancelipid profileoxidative stresspostmenopause

Identifiers

PMID41978180
PMCPMC13074984

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.