Evidence map›Paper›PMID 41978371›Full record

ArticleeLife2026

Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns.

Ken-Ichiro F Kamei, Koseki J Kobayashi-Kirschvink, Takashi Nozoe, Hidenori Nakaoka, Miki Umetani, Yuichi Wakamoto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Live-cell omics with Raman spectroscopy.Microscopy (Oxford, England) · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ken-Ichiro F KameiDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0009-0002-8026-4454
Koseki J Kobayashi-KirschvinkDepartment of Medicine, The University of Chicago, Chicago, United States.ORCID https://orcid.org/0000-0001-6590-3823
Takashi NozoeDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-2556-6484
Hidenori NakaokaDepartment of Optical Imaging, Advanced Research Promotion Center Tokushima University, Tokushima, Japan.ORCID https://orcid.org/0000-0001-8465-5853
Miki UmetaniDepartment of Biology, New York University, New York, United States.ORCID https://orcid.org/0000-0002-3171-4327
Yuichi WakamotoDepartment of Basic Science, Graduate School of Arts and Sciences, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6233-0844

Funding

Japan Science and Technology Agency JPMJCR1927Japan Science and Technology Agency JPMJER1902Japan Society for the Promotion of Science 19J22448Japan Society for the Promotion of Science 21K20672
6 · The paper itself

Abstract

Cells can adapt to various environments by changing their biomolecular profiles while maintaining physiological homeostasis. What organizational principles in cells enable the simultaneous realization of adaptability and homeostasis? To address this question, we measure Raman scattering light from

Indexed as

Escherichia coliProteomeSpectrum Analysis, RamanHumansProteomeE. coligeneticsgenomicshumanlow dimensionalityM. bovisM. tuberculosisphysics of living systemsproteomeRamanS. cerevisiaeS. pombestoichiometry conservation

Identifiers

PMID41978371
PMCPMC13078787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.