Evidence map›Paper›PMID 41978617›Full record

ArticleInfection and drug resistance2026

Clinical Characteristics and Early Risk Factors for Severe

Jia An, Shuling Du, Shuping Yu, Ling Xu, Yu Song, Li Dong, Shunying Zhao

Abstract read
In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Glycyrrhizin alleviatesJournal of thoracic disease · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jia AnDepartment II of Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China National Clinical Research Center of Respiratory Disease, Beijing, 100045, People's Republic of China.
Shuling DuPediatric Emergency, The Seventh Medical Centre, Chinese PLA General Hospital, Beijing, 100700, People's Republic of China.
Shuping YuMedical Security Cente, The Seventh Medical Centre, Chinese PLA General Hospital, Beijing, 100700, People's Republic of China.
Ling XuChildren's Outpatient and Emergency Department, The Seventh Medical Centre, Chinese PLA General Hospital, Beijing, 100700, People's Republic of China.
Yu SongChildren's Outpatient and Emergency Department, The Seventh Medical Centre, Chinese PLA General Hospital, Beijing, 100700, People's Republic of China.
Li DongChildren's Outpatient and Emergency Department, The Seventh Medical Centre, Chinese PLA General Hospital, Beijing, 100700, People's Republic of China.
Shunying ZhaoDepartment II of Respiratory Medicine, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China National Clinical Research Center of Respiratory Disease, Beijing, 100045, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: This retrospective analysis included 417 hospitalized children diagnosed with MPP, comprising 210 children with SMPP and 207 children with general Results: Children with SMPP had longer hospitalization and higher frequencies of extrapulmonary complications. Their C-reactive protein (CRP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and D-dimer (DD) levels were markedly higher. Imaging findings more often demonstrated lobar pneumonia, atelectasis, and pleural effusion. Multivariate logistic regression analysis identified CRP, AST, LDH, and DD as independent risk factors for SMPP. ROC analysis indicated that LDH greater than 286.5 U/L, DD greater than 0.1965 mg/L, and AST greater than 25.05 U/L were strong predictors of SMPP. Conclusion: The clinical and laboratory profiles of children with SMPP differed significantly from those with GMPP. CRP, AST, LDH, and DD function as important indicators for early identification and assessment of disease severity, supporting clinical decision making. Early monitoring of these parameters enables timely recognition of high-risk patients and may improve clinical management and prognosis.

Indexed as

clinical characteristicsinflammatory factorsMycoplasma pneumoniae pneumoniapredictive indicatorsrisk factors

Identifiers

PMID41978617
PMCPMC13070195

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.