Evidence mapPaperPMID 41978720Full record

ReviewInternational journal of nanomedicine2026

From Nature to Nanomedicine: Engineered Plant-Derived Nanovesicles for Skin Disease.

Zongshi Yue, Jinping Yin, Yanan Li

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zongshi Yue *Department of Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Jinping Yin *State Key Laboratory of Molecular Oncology and Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People's Republic of China.
Yanan LiDepartment of Respiration, Children's Medical Center, The First Hospital of Jilin University, Changchun, 130021, People's Republic of China.ORCID 0000-0002-7598-0790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant-derived nanovesicles (PDN), as a novel class of natural nanocarriers, possess excellent biocompatibility and the capacity to load various bioactive components, offering new perspectives for the treatment of skin diseases. However, natural PDN suffer from limited skin penetration and weak targeting ability. By applying engineering strategies such as chemical modification and membrane hybridization, these intrinsic limitations can be effectively overcome, thereby markedly enhancing their therapeutic efficacy against skin diseases. This review provides a systematic summary of the fundamental characteristics and engineering strategies of PDN. Based on the latest research advances, we also outline their therapeutic applications across various skin diseases, including inflammatory, infectious, wounds, aging-related, pigmentary, and tumors. In addition, we propose lesion-adapted administration strategies tailored to different skin diseases. We further highlight the major translational challenges and future opportunities of PDN, providing insight into how these engineered natural nanocarriers may reshape precision and next-generation therapies for skin diseases.

Indexed as

NanomedicinePlantsSkin DiseasesAnimalsHumansadvanced delivery systembiomimetic nanocarriersdermatological diseasesengineered nanovesiclesexosome-like nanovesicles

Identifiers

PMID41978720
PMCPMC13070027

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.