Trial reportClinical ophthalmology (Auckland, N.Z.)2026
Laughter Exercise for Symptomatic Improvement in Dry Eye Following Cataract Surgery: A Randomized Controlled Trial.
Trial report in Clinical ophthalmology (Auckland, N.Z.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The effectiveness of laughter exercise in dry eye disease (DED) remains uncertain. This study aimed to evaluate the efficacy and safety of laughter exercise in patients with DED who had undergone cataract surgery. Methods: This was a parallel-group, randomized controlled trial. A total of 72 participants were randomly assigned to either the laughter exercise group (n=36) or the control group (n=36). Participants in the intervention group performed guided laughter exercises four times a day for 4 weeks. Outcomes were measured preoperatively and at 1, 4, and 12 weeks postoperatively. The primary outcome was the mean change in dry eye symptom scores. Secondary outcomes included tear meniscus height, tear break-up time, health status scores (both physical (PCS) and mental (MCS) component summaries), intervention participation, satisfaction, and incidence of adverse events. Results: Repeated measures ANOVA was used to analyze dry eye symptom scores. The results showed a significant group×time interaction ( Conclusion: Laughter exercises can relieve dry eye symptoms in patients who have undergone cataract surgery and improve their physical and mental health. Although this therapy has no significant effect on improving objective clinical symptoms, it can be a safe and effective adjuvant treatment.
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