Evidence map›Paper›PMID 41981320›Full record

ArticleBioresources and bioprocessing2026

Maximizing Populus tremula biomass conversion: synergistic pretreatment effects on sugars release and lignin recovery.

Sharib Khan, Vahur Rooni, Daniel Rauber, Nikki Sjulander, Markus Gallei, Christopher W M Kay, Sabarathinam Shanmugam, Timo Kikas

Abstract read
In one paragraph

Article in Bioresources and bioprocessing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sharib KhanChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Tartu, Estonia.ORCID http://orcid.org/0000-0003-3203-5462
Vahur RooniChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Tartu, Estonia.
Daniel RauberPolymer Chemistry, Saarland University, Campus C4.2, 66123, Saarbrücken, Germany.ORCID http://orcid.org/0000-0003-0488-4344
Nikki SjulanderChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Tartu, Estonia.
Markus GalleiPolymer Chemistry, Saarland University, Campus C4.2, 66123, Saarbrücken, Germany. markus.gallei@uni-saarland.de.ORCID http://orcid.org/0000-0002-3740-5197
Christopher W M KayPhysical Chemistry and Chemistry Education, Saarland University, Campus B2.2, 66123, Saarbrücken, Germany.
Sabarathinam ShanmugamChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Tartu, Estonia. sabarathinam.shanmugam@emu.ee.ORCID http://orcid.org/0000-0002-3032-9128
Timo KikasChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Tartu, Estonia. timo.kikas@emu.ee.ORCID http://orcid.org/0000-0003-0076-8047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition to a forest-based economy relies on sustainable alternatives that can efficiently convert renewable resources into chemical and material products. Sugar-centered wood fractionation processes, also called modern biorefineries, offer significant potential as a renewable precursor for the substitution of petrochemical derivatives. However, unlocking the full potential of advanced biorefineries requires optimized pretreatment strategies to valorize all biomass-side streams. This work evaluated the distinctive and connective applications of nitrogen explosive decompression (NED), protic ionic liquid (PIL), and alkaline pretreatments for the production of monosaccharides, oligosaccharides, and high value lignin from aspen (Populus tremula) biomass within a biorefinery context. Each pretreatment method uniquely influenced biomass fractionation, affecting the hemicellulose and cellulose dissolution, delignification, and the physicochemical properties of the remaining cellulose and lignin components. The findings indicate that PIL pretreatment alone yielded 56% monomeric sugars upon saccharification. Additionally, the combinatorial PIL-NED and Alkaline-NED pretreatment was superior for lignin removal, achieving 68% and 85% delignification while concurrently generating valuable side streams. Henceforth, integrated PIL-NED collaborative approach presents a considerable cost and efficiency advantage over conventional biorefinery pretreatments, offering a promising pathway for the co-production of monosaccharides and high-quality lignin.

Indexed as

BiorefineryLigninLignocellulosic biomassProtic ionic liquidSugars

Identifiers

PMID41981320
PMCPMC13079260

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.