Evidence map›Paper›PMID 41981367›Full record

Observational studyAlzheimer's & dementia : the journal of the Alzheimer's Association2026

The Canadian multi-ethnic research on aging (CAMERA) study: Design, participant characteristics, and preliminary findings.

Tulip Marawi, Harleen Rai, Rohina Kumar, Katie L Vandeloo, Rachel Yep, Madeline Wood Alexander, Silina Z Boshmaf, Sarah-Mei Chen, Georgia Gopinath, Simran Malhotra and 11 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Tulip MarawiHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Harleen RaiHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Rohina KumarHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Katie L VandelooHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Rachel YepHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Madeline Wood AlexanderHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Silina Z BoshmafHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Sarah-Mei ChenHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Georgia GopinathHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Simran MalhotraHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Angelina ZhangHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Alexander J NymanHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Lucas Xavier PerriHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Valery SitHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Tallinn F L SplinterHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Douglas P MunozDepartment of Biomedical & Molecular Sciences, Queen's University, Kingston, Canada.
Walter SwardfagerHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Jennifer D RyanRotman Research Institute, Baycrest Health Sciences, Toronto, ON, Canada.
Sandra E BlackHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Maged GoubranHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.
Jennifer S RabinHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, ON, Canada.

Funding

the Alzheimer's Association AARG-23-1144933the Canadian Institutes of Health Research 173253
6 · The paper itself

Abstract

introductionSouth Asian and Chinese individuals are the largest and fastest-growing ethnoracial groups in Canada, yet they remain underrepresented in dementia research. To address this gap, we established the CAnadian Multi-Ethnic Research on Aging (CAMERA) study.

methodsCAMERA is a longitudinal observational study conducted in Toronto, Canada, enrolling 300 adults aged 55-85 who self-identify as South Asian, Chinese, or non-Hispanic White (NHW). Participants complete in-person visits at baseline, Year 3, and Year 5, which include clinical and cognitive assessments, brain magnetic resonance imaging (MRI), and blood-based biomarkers. Annual remote questionnaires track health and lifestyle factors.

resultsAmong the first 200 participants, vascular and metabolic profiles differed across groups. In addition, South Asian and Chinese participants reported greater cognitive concerns than NHW participants and had lower Montreal Cognitive Assessment (MoCA) scores. The latter was driven primarily by language-heavy and culturally dependent items. Eye-tracking measures did not differ across groups. DISCUSSION: CAMERA provides a deep phenotyping framework to investigate dementia risk and resilience factors in Asian Canadians.

Indexed as

AgingAgedAged, 80 and overAsian PeopleAsia, SouthernBrainCanadaCanadian Longitudinal Study on AgingChinaDementiaEthnicityFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleADRDAlzheimer's diseaseAsianChinesedementiaethnoracial diversitySouth Asian

Identifiers

PMID41981367
PMCPMC13079077

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.