Evidence map›Paper›PMID 41981492›Full record

Trial reportBMC geriatrics2026

Effects of low-load resistance training with blood flow restriction and swallowing training on sarcopenic dysphagia in community-dwelling older people in China: a randomised controlled trial protocol.

Yue Xing, Xiangfeng He, Yanping Song, Nan Chen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC geriatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yue Xing *Department of Rehabilitation, Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Xiangfeng He *Department of Rehabilitation, Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China.
Yanping SongDepartment of Rehabilitation, Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China. songyanpingf@163.com.
Nan ChenDepartment of Rehabilitation, Chongming Hospital, Shanghai University of Medicine and Health Sciences, Shanghai, China. chennanreh2020@126.com.

Funding

Center for Whole Population Whole Lifecycle Cohort Clinical Research 22MC2022001Research on Early Screening and Intervention Strategies for Cognitive Impairment in the Community-dwelling older people with Sarcopenia the 20254Z0006the surface project of National Natural Science Foundation of China, Mechanism of BCAT2-mediated inhibition of iron death by branched-chain amino acid metabolism in the intestinal ora of P . merdae to alleviate the progression of sarcopenia No. 82372575
6 · The paper itself

Abstract

backgroundSarcopenic dysphagia, characterised by dysphagia resulting from sarcopenia with decline of skeletal muscles and swallowing-related muscle strength and mass, poses a significant healthcare and economic burden on families and society. Swallowing training (ST) has been proven to improve dysphagia in older people with neurological disorders such as stroke. However, the effects of this training on people with sarcopenic dysphagia are limited. Considering the significant effect of sarcopenia on the pathogenesis of sarcopenic dysphagia, resistance training was incorporated into the conventional ST protocol to potentially enhance outcomes of interventions and provide additional benefits for older people with sarcopenic dysphagia. This study aims to compare the effects of resistance training combined with ST and ST alone in older people with sarcopenic dysphagia and to explore the underlying mechanism.

methodsThis study is a 12-week randomised, assessors-blind controlled trial. A total of 33 community-dwelling older people with sarcopenic dysphagia will be randomised into one of the following three groups: low-load resistance training with blood flow restriction (LRT-BFR) + ST group, ST group and control group. The LRT-BFR + ST group will receive combined intervention, whereas the ST group will receive ST alone. The control group will receive health education only. Swallowing-related muscle mass and strength, swallowing function, physical outcomes associated with sarcopenia, nutritional status, quality of life, psychological outcomes and blood biomarkers will be assessed at baseline, post-intervention (12 weeks) and follow-up (24 weeks). DISCUSSION: This randomised controlled trial systematically evaluates the efficacy of a novel intervention combining LRT-BFR and ST for community-dwelling older people with sarcopenic dysphagia whilst exploring the potential mechanisms. This study will assess whether resistance training augments ST outcomes and provides supplementary benefits for older people with sarcopenic dysphagia.

trial registrationThe protocol was registered in the Chinese Clinical Trial Registry (ChiCTR2500099265, registration date: March 20th, 2025). Any amendments to the study protocol will be reported at www.chictr.org.cn/showproj.html?proj=261525 .

Indexed as

Blood Flow Restriction TherapyDeglutitionDeglutition DisordersIndependent LivingResistance TrainingSarcopeniaAgedAging in PlaceChinaFemaleHumansMaleSingle-Blind Methodblood flow restrictionresistance trainingSarcopenic dysphagiaswallowing training

Identifiers

PMID41981492
PMCPMC13200429

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.